Copyright ©The Author(s) 2022.
World J Gastroenterol. Jul 28, 2022; 28(28): 3586-3594
Published online Jul 28, 2022. doi: 10.3748/wjg.v28.i28.3586
Table 1 Comparison of liver biopsy methods1

Percutaneous liver biopsy
Transjugular liver biopsy
Endoscopic ultrasound-guided liver biopsy
Most common form of anesthesiaLocalModerate sedationModerate sedation, deep sedation
ImagingFluoroscopy, ultrasoundFluoroscopyUltrasound
Capsular punctureYesNoYes
Ability to evaluate focal hepatic lesionsNoNoYes
Liver lobe accessRightRightRight, left
ContraindicationsINR > 1.5, body habitus, significant ascitesVenous thrombosis, cholangitisINR > 1.5
Post-procedural pain+++++
Post-procedural minor bleeding+++
Adverse event rate+++
Post-procedural recovery time++++++
Specimen length+++++
Total complete portal tracts++++++
Procedure cost++++++
Institutional availability++++++