Effects of acute kidney injury on acute pancreatitis patients’ survival rate in intensive care unit: A retrospective study

Table 1 Baseline and clinical data of patients

	AKI (n = 72)	Non-AKI (n = 67)	Z/χ2	P value
Age	45.00 (17.50)	44.00 (21.00)	-0.07	0.94
Gender			6.745	0.009
Male	50	32
Female	22	35
BMI	24.45 (2.38)	23.80 (2.60)	-1.20	0.23
APACHE II Score	18.00 (7.75)	9.00 (7.00)	-7.47	< 0.01
SOFA Score	9.00 (6.00)	4.00 (4.00)	-6.50	< 0.01
GCS Score	15.00 (3.00)	15.00 (0.00)	-2.71	0.01
MV			10.94	0.001
Yes	46	24
No	26	43
Abdominal puncture drainage			0.19	0.66
Yes	36	36
No	36	31
Gallbladder puncture drainage			2.36	0.12
Yes	17	9
No	55	58
Vasopressor infusion			26.84	< 0.01
Yes	21	18
No	51	49
RRT
Yes	44	20	13.651	< 0.01
No	28	47

AKI: Acute kidney injury; APACHE II: Acute Physiology and Chronic Health Evaluation II; BMI: Body mass index; GCS: Glasgow Coma Scale; MV: Mechanical ventilation; RRT: Renal replacement therapy; SOFA: Sequential Organ Failure Assessment.

Table 2 Vasopressor infusion

	AKI, n = 72	Non-AKI, n = 67	χ2	P value
Types of vasopressors			27.44	< 0.01
No	21	49
1	34	14
≥ 2	17	4
Norepinephrine infusion			35.35	< 0.01
Yes	49	17
No	23	50
Adrenaline infusion			12.75	< 0.01
Yes	15	1
No	57	66
Vasopressor infusion			26.84	< 0.01
Yes	51	18
No	21	49

AKI: Acute kidney injury.

Table 3 Analysis of prognostic indicators

	AKI, n = 72	Non-AKI, n = 67	Z/t/Wald	P value	OR
Prognosis of SICU			9.54	0.002	0.23
cure	48	60
other	24	7
Prognosis of in-hospital			11.33	0.001	0.21
cure	46	60
other	26	7
Duration of MV	34.00 (87.75)	0.00 (18.00)	-3.92	< 0.01
Maximum values of IPP	24.50 (10.00)	18.00 (10.00)	-5.39	< 0.01
Mean values of IPP	21.40 (6.82)	15.29 (4.73)	6.175	< 0.01
Maximum values of body temperature	37.80 (1.20)	37.50 (1.00)	-2.00	0.05
Mean values of body temperature	37.00 (0.50)	37.00 (0.30)	-0.59	0.56
Maximum values of PCT	16.28 (21.12)	2.87 (9.28)	-5.96	< 0.01
Mean values of PCT	8.52 (11.52)	1.58 (4.20)	-6.42	< 0.01
Maximum serum levels of creatinine	284.35 (215.73)	87.60 (47.80)	-9.94	< 0.01
Mean serum levels of creatinine	197.45 (172.10)	65.60 (29.60)	-9.48	< 0.01
Minimum platelet count	93.00 (87.75)	137.00 (73.00)	-3.18	< 0.01
Mean platelet count	174.40 (112.15)	198.00 (103.60)	-1.64	0.10
Hospital day	9.00 (12.75)	8.00 (11.00)	-0.07	0.94
Dose of norepinephrine	16.00 (52.00)	0.00 (4.00)	-5.11	< 0.01
Dose of adrenaline	0.00 (0.00)	0.00 (0.00)	-3.58	< 0.01

AKI: Acute kidney injury; MV: Mechanical ventilation; IPP: Intra-peritoneal pressure; OR: Odds ratio; PCT: Procalcitonin; SICU: Surgical intensive care unit.

Table 4 Analysis of the related factors influencing acute pancreatitis patients’ survival rate

	B	SE	Wald	df	P value	Exp (B)
BMI	1.4904	0.6467	5.3105	1.0000	0.0212	4.4387
Mean values of IPP	2.6477	0.6217	18.1355	1.0000	0.0000	14.1211
Minimum platelet count	-1.2285	0.6125	4.0237	1.0000	0.0449	0.2927
Hospital day	-1.8571	0.5965	9.6913	1.0000	0.0019	0.1561
Constant	-0.9863	0.8689	1.2883	1.0000	0.2564	0.3730

BMI: Body mass index; IPP: Intra-peritoneal pressure; SE: Standard error.

Table 5 Area under the receiver operating characteristic curve

Variables	Area	SE	Asymptotic, P value	Asymptotic 95%CI
				Lower bound	Upper bound
With AKI	0.896	0.033	0	0.831	0.961
Without AKI	0.891	0.037	0	0.819	0.963

AKI: Acute kidney injury; CI: Confidence interval; SE: Standard error.