Review
Copyright ©The Author(s) 2021.
World J Gastroenterol. Jun 14, 2021; 27(22): 2963-2978
Published online Jun 14, 2021. doi: 10.3748/wjg.v27.i22.2963
Table 1 Upper gastrointestinal endoscopic and microscopic presentations in ulcerative colitis
Classification
Presentations of UGI in UC
EndoscopyErythema
Edema
Inconspicuous vascular morphology
Granularity
Friability
Oral ulcers, superficial ulcers
Bamboo joint-like appearance
White spots
Purulent deposits
MicroscopyEsophagusEsophageal ulcers
Esophagitis
Unspecified/nonspecific
StomachUnspecified chronic gastritis
Lymphocytic gastritis
FEG
Ulcers
DuodenumDiffuse chronic duodenitis in the presence of mucosal dilatation
Structural deformation
Intraepithelial lymphocytic disease with normal mucosal structure
Table 2 Clinical characteristics of esophageal ulcer complicated with ulcerative colitis
Case No.
Ref.
Age
Gender
Duration of UC
Esophageal ulcer
Location
Symptoms
Treatment
1Margoles et al[23], 196128M17 yrWeb formationMiddle esophagusNoNA
2Knudsen et al[36], 196715M2 yrSevere esophagitisLower esophagusParasternal chest pain and dysphagiaPSL
3Rosendorff et al[35], 196723M5 yrShallow ulceration with gross diffuse irregularityMiddle and lower esophagusDysphagiaPSL
4Christopher et al[37], 196921F0Active ulcerative esophagitisNANANA
5Christopher et al[37], 196919M0Marked ulcerative esophagitisNASubstenal pain and dysphagiaNA
6Christopher et al[37], 196926M2 moEsophageal ulcerations with perforaton into theanterior mediastinumNADysphagia, fever, hypotensionNA
7Christopher et al[37], 196914F5 yrNecrotizing fibrinopurulent ulcerationNANANA
8Christopher et al[37], 196924M9 yrUlcerative and membranous esophagitisNANausea, vomiting and hematemesisNA
9Zimmerman et al[38], 198421M3 yrMultiple friable ulcerationsWhole esophagusSevere odynophagia and dysphagiaPSL, tetracycline
10Konishi et al[40], 199847F0Multiple irregular esophageal ulcersWhole esophagusAnterior chest pain and dysphagia5ASA, H2blocker
11Asakawa et al[44], 200018F7 yrLongitudinal esophageal ulcer with hemorrhageMiddle and lower esophagusSore throat and pain on swallowingPSL
12Ikeda et al[42], 200018M1 yrPunched-out esophageal ulcerMiddle esophagusSore throat and anterior chest painPSL
13Higashi et al[41], 200419M0Punched-out esophageal ulcerMiddle esophagusGeneral fatiguePSL, SASP
14Sato et al[45], 200533M0Punched-out esophageal ulcerMiddle and lower esophagusAnterior chest pain and dysphagiaPPI
15Izawa et al[39], 201552F3 yrPunched-out esophageal ulcerMiddle esophagusAnterior chest pain on swallowingPSL
16Kuroki et al[43], 201947M3 yrNecrosisLower esophagusEpigastric painPPI
17Kuroki et al[43], 201953MNANecrosisMiddle and lower esophagusHematemesisPPI
18Tominaga et al[24], 202016F0An esophageal ulcer with aphthaeMiddle esophagusChest painPSL
19Tominaga et al[24], 202019F0Longitudinal esophageal ulcerLow esophagusChest pain on swallowingPSL
20Ours24M1 yrMultiple ulcerative lesionsMultiple lesionsBurning sensationRemicade