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©The Author(s) 2020.
World J Gastroenterol. Dec 14, 2020; 26(46): 7405-7415
Published online Dec 14, 2020. doi: 10.3748/wjg.v26.i46.7405
Published online Dec 14, 2020. doi: 10.3748/wjg.v26.i46.7405
Table 1 Nutrition supply postoperatively
Group | Nutritional support | POD 1 | POD 2 | POD 3 | POD 4 | POD 5 | POD 6 |
TPN group | PN | 10 kcal/kg | 20 kcal/kg | 30 kcal/kg | 35 kcal/kg | 35 kcal/kg | 35 kcal/kg |
EN | 0 | 0 | 0 | 0 | 0 | 0 | |
EEN + PN group | PN | 10 kcal/kg | 10 kcal/kg | 10 kcal/kg | 5 kcal/kg | 0 | 0 |
EN | 0 | 10 kcal/kg | 20 kcal/kg | 30 kcal/kg | 35 kcal/kg | 35 kcal/kg |
Table 2 Baseline data before operation
Group | Number of cases | Age in yr, mean ± SD | Gender of cases, M/F | NRS score, mean ± SD | Total bilirubin as µmol/L, mean ± SD | Jaundice duration in d, mean ± SD | PTCD cases |
TPN group | 30 | 58.90 ± 7.42 | 18/12 | 4.03 ± 0.78 | 100.26 ± 19.18 | 21.26 ± 9.16 | 16 |
EEN + PN group | 26 | 59.08 ± 7.64 | 15/11 | 4.08 ± 0.78 | 96.50 ± 18.01 | 18.96 ± 8.89 | 18 |
t or χ2 | 0.089 | 0.031 | 0.239 | 0.753 | 0.950 | 1.476 | |
P value | 0.9291 | 0.8612 | 0.8121 | 0.4551 | 0.3461 | 0.2242 |
Table 3 Comparison of operation methods and relevant data
Basic data | EEN + PN group, n = 26 | TPN group, n = 30 | t or χ2 | P value |
Operation methods by case | ||||
Pancreatoduodenectomy | 12 | 20 | 2.393 | 0.1222 |
Choledochojejunostomy | 14 | 10 | ||
Operative duration in h, mean ± SD | 3.27 ± 0.88 | 2.84 ± 0.90 | 1.802 | 0.0771 |
Amount of bleeding in mL, mean ± SD | 476.00 ± 187.71 | 524.00 ± 169.61 | 1.005 | 0.3191 |
NRS score on the first day after operation by score, mean ± SD | 4.25 ± 0.74 | 4.21 ± 0.88 | 0.183 | 0.8561 |
Table 4 The incidence of abdominal distention, bile leakage, and infection of operation site in the two groups, n (%)
Cases | Abdominal distention | Bile leakage | Surgical site infection | |
TPN group | 30 | 4 (13.33) | 4 (13.33) | 5 (16.67) |
EEN + PN group | 26 | 11 (42.31) | 2 (7.96) | 2 (7.96) |
Total | 56 | 15 (26.79) | 6 (10.71) | 7 (12.50) |
P value | 0.018 | 0.675 | 0.431 |
Table 5 Comparison of recovery time of intestinal function, hospitalization time, and total cost of hospitalization, mean ± standard deviation
Cases | Recovery time of intestinal function after operation in h | Postoperative hospital stay in d | Cost of hospitalization in RMB | |
TPN group | 30 | 72.0 ± 12.9 | 9.7 ± 1.5 | 109036.69 ± 7949.71 |
EEN + PN group | 26 | 51.2 ± 4.4 | 8.7 ± 0.8 | 87852.37 ± 9127.04 |
t | 7.828 | 3.043 | 9.285 | |
P value | < 0.001 | 0.004 | < 0.001 |
- Citation: Ma BQ, Chen SY, Jiang ZB, Wu B, He Y, Wang XX, Li Y, Gao P, Yang XJ. Effect of postoperative early enteral nutrition on clinical outcomes and immune function of cholangiocarcinoma patients with malignant obstructive jaundice. World J Gastroenterol 2020; 26(46): 7405-7415
- URL: https://www.wjgnet.com/1007-9327/full/v26/i46/7405.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i46.7405