Case Control Study
Copyright ©The Author(s) 2020.
World J Gastroenterol. Dec 14, 2020; 26(46): 7352-7366
Published online Dec 14, 2020. doi: 10.3748/wjg.v26.i46.7352
Table 1 Demographic characteristics of ulcerative colitis patients and controls
Variable
UC patients, n = 100
HC, n = 56
P value
Age [mean (SD), yr]45.5 (14.2)45.8 (10.0)0.8731
Sex (female: male)57:4332:240.9862
Smoker, n (%)45 (45.0) 21 (37.5)0.3632
BMI [mean (SD), kg/m2]21.2 (3.4)20.4 (2.1)0.1011
25 (OH) D [mean (SD), nmol/L]13.7 (2.8)16.2 (2.5)< 0.0011
Disease Location, n (%)
Ulcerative proctitis (E1)8 (8.0)--
Left-sided colitis (E2)54 (54.0)--
Extensive colitis (E3)38 (38.0)--
Severity of UC, n (%)
Mild29 (29.0)--
Moderate32 (32.0)--
Severe39 (39.0)--
Current medications, n (%)
SASP/5-ASA80 (80.0)--
Immunosuppressants2 (2.0)--
Steroids31 (31.0)--
Biologics4 (4.0)--
Others22 (22.0)--
Duration of disease mean (SD), yr5.4 (6.0)--
Table 2 Laboratory indexes characteristics of ulcerative colitis patients with different disease activity
Indexes
Mild activity, n = 29
Moderate activity, n = 32
Severe activity, n = 39
Serum vitamin D (ng/mL)14.8 ± 2.414.2 ± 2.411.7 ± 3.1
WBC (109/L)6.90 (4.53-12.81)7.13 (0.32-6.02)7.13 (3.28-17.59)
CRP (mg/L)1.51 (0.38-66.23)9.90 (0.30-168.78)70.67 (1.44-190.07)
ESR (mm/h)8 (3-34)23 (3-95)41 (7-127)
ALP (U/L)81 (49-140)85 (40-602)77.50 (53-109)
PLT (109/L)222 (113-363)260 (130-518)286 (125-500)
HGB (g/L)137 (74-155)115 (59-164)115 (55-149)
ALB (g/L)42.11 ± 4.9737.25 ± 6.1331.31 ± 4.79
Ca (mmol/L)2.31 (1.01-2.63)2.23 (1.67-2.49)2.06 (1.82-2.31)
P (mmol/L)1.12 ± 0.201.17 ± 0.211.11 ± 0.27
Mayo score5 (3-5)8 (6-10)11.5 (11.0-12.0)