Copyright
©The Author(s) 2020.
World J Gastroenterol. Aug 28, 2020; 26(32): 4802-4816
Published online Aug 28, 2020. doi: 10.3748/wjg.v26.i32.4802
Published online Aug 28, 2020. doi: 10.3748/wjg.v26.i32.4802
Table 1 Sites and frequency [n/n (%)] of distant metastasis and local tumor infiltration of MIA-PaCa-2 cells
| MIAPaCa-2 (SC) | MIAPaCa-2 (OrT) | |||
| B-NDG | ZZU001 | B-NDG | ZZU001 | |
| Distant metastasis | ||||
| Liver | - | - | 3/5 (60) | 5/5 (100) |
| Lung | - | 5/5 (100) | - | 5/5 (100) |
| Retroperitoneum | - | - | 3/5 (60) | 5/5 (100) |
| Mesentery | - | - | 3/5 (60) | 5/5 (100) |
| Diaphragm | - | - | 2/5 (40) | 2/5 (40) |
| Spleen | - | - | 2/5 (40) | - |
| Stomach | - | - | - | 1/5 (20) |
| Kidney | - | 2/5 (40) | - | 5/5 (100) |
| Adrenal gland | - | 1/5 (20) | - | 2/5 (40) |
| Local infiltration | ||||
| Spleen | - | - | 3/5(60) | 4/5 (80) |
| Stomach | - | - | 1/5 (20) | 3/5 (60) |
| Liver (hilus) | - | - | 3/5 (60) | 5/5 (100) |
| Kidney (hilus) | - | - | - | 1/5 (20) |
| Retroperitoneum | - | - | 3/5 (60) | 5/5 (100) |
| Bowel | - | - | 3/5 (60) | 5/5 (100) |
| Mesentery (adjacent to pancreas) | - | 4/5 (80) | 5/5 (100) | |
| Signs of tumor burden | ||||
| Ascites | - | - | 3/5 (60) | 3/5 (60) |
| Jaundice | - | - | 2/5 (40) | 3/5 (60) |
| Ileus | - | - | - | 2/5 (40) |
| Cachexia | - | - | 1/5 (20) | 3/5 (60) |
Table 2 Sites and frequency [n/n (%)] of distant metastasis of four different human pancreatic cancer cell lines
| Panc-1 (SC) | SUIT-2 (SC) | Patu8988T (SC) | Capan-1 (SC) | |
| ZZU001 | ZZU001 | ZZU001 | ZZU001 | |
| Distant metastasis | ||||
| Liver | - | 1/3 (33) | 3/5 (60) | - |
| Lung | 5/5 (100) | 3/3 (100) | - | 5/5 (100) |
| Retroperitoneum | - | - | - | - |
| Mesentery | - | - | - | - |
| Diaphragm | - | - | - | - |
| Spleen | - | - | - | - |
| Stomach | - | - | - | - |
| Kidney | - | 1/3 (33) | 1/5 (20) | - |
| Adrenal gland | - | - | - | - |
- Citation: Miao JX, Wang JY, Li HZ, Guo HR, Dunmall LSC, Zhang ZX, Cheng ZG, Gao DL, Dong JZ, Wang ZD, Wang YH. Promising xenograft animal model recapitulating the features of human pancreatic cancer. World J Gastroenterol 2020; 26(32): 4802-4816
- URL: https://www.wjgnet.com/1007-9327/full/v26/i32/4802.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i32.4802