Epidemiology of inflammatory bowel disease in South America: A systematic review

Table 1 Inclusion criteria

Inclusion criteria
Population	Adult (> 18 yr old)
Language	English
Date range	January 1990 to December 2018
Location	South America
Type of study	Randomised controlled trials, cohort studies, cross sectional studies, case series, and observational studies

Table 2 Characteristics of included studies

Ref.	Country	Type of study	Type of IBD	Year data set	n	Average patient age	Specific group
Linares et al[16]	Argentina	Registry	UC/CD	1987-1993	39	38	Multicentre
Salgado et al[18]	Brazil	Case-control	CD	2017	145-163	NR	Single Centre
Lima Martins et al[13]	Brazil	Registry	UC/CD	2012-2014	1048	NR	Multicentre
Queiroz et al[20]	Brazil	Case-control	UC/CD	2017	85/541	40.0	Single Centre
Santos et al[21]	Brazil	Registry	UC/CD	2016	556	49.7	Single Centre
da Silva et al[22]	Brazil	Cross-sectional	UC	2011-2012	267	33.4	Multicentre
Parente et al[12]	Brazil	Registry	UC/CD	1988-2012	256	25.2	Multicentre
Victoria et al[11]	Brazil	Registry	UC/CD	1986-2005	115	38.0	Multicentre
Santana et al[23]	Brazil	Cross-sectional	CD	2006	65	37.3	Single Centre
Torres Udos et al[24]	Brazil	Cross-sectional	CD	1992-2007	90	33	Single Centre
Cohen et al[25]	Brazil	Cross-sectional	UC/CD	2008	50	42.2	Single Centre
Hardt et al[26]	Brazil	Cross-sectional	CD	2000-2012	175	35.5	Multicentre
Santana et al[27]	Brazil	Cross-sectional	CD	2005	47	38.5	Single Centre
de Barros et al[28]	Brazil	Cross-sectional	UC/CD	2012-2013	40	37.8	Single Centre
Simian et al[17]	Chile	Registry	UC/CD	2012-2015	716	36	Single Centre
Alvarez-Lobos et al[19]	Chile	Case-control	CD	2010-2012	94/90	35.5	Single Centre
Barreto et al[15]	Colombia	Registry	UC/CD	1991-2006	26	40	Single Centre
Buenavida et al[16]	Uruguay	Registry	UC/CD	2007-2008	34	40.7	Multicentre

UC: Ulcerative colitis; CD: Crohn’s disease; IBD: Inflammatory bowel disease; NR: Not reported.