How does Helicobacter pylori cause gastric cancer through connexins: An opinion review

doi:10.3748/wjg.v25.i35.5220

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Opinion Review

World J Gastroenterol. Sep 21, 2019; 25(35): 5220-5232
Published online Sep 21, 2019. doi: 10.3748/wjg.v25.i35.5220

Table 1 Connexin expression in the gastrointestinal tract and liver

Tissue	Cell type	Cx members	Ref.
Liver
	Hepatocytes	Cx32/Cx26	[161]
	Kupffer cells	Cx43/Cx26	[162-164]
	Stellate cells	Cx43/Cx26	[163-165]
	Sinusoidal endothelial cells	Cx43/Cx32/Cx26	[163,164,166,167]
	Portal vein endothelial cells	Cx43/Cx40/Cx37	[168-170]
	Hepatic artery endothelial cells	Cx43/Cx40/37	[168-170]
	Cholangiocytes	Cx43/Cx32	[171,172]
Stomach		Cx45/Cx43/Cx40/Cx37/Cx32/Cx26	[49-57,146]
	Foveolar cells	Cx32	[173]
Small intestine
	Musculus externa cells	Cx43/Cx40	[51]
	Myenteric plexus cells	Cx45/Cx43/Cx40/Cx36	[51,174,175]
	Epithelial cells	Cx43/Cx37/Cx32	[51,176,177]
	Interstitial cells of Cajal	Cx43	[51,178]
Colon
	Musculus externa cells	Cx43/Cx40/Cx26	[51,179]
	Myenteric plexus cells	Cx45/Cx43/Cx40/Cx36	[51,175]
	Epithelial cells	Cx43/Cx37/Cx32/Cx26	[177,180-183]
	Muscularis mucosal cells	Cx43	[51]
	Interstitial cells of Cajal	Cx43	[178]

Citation: Li H, Xu CX, Gong RJ, Chi JS, Liu P, Liu XM. How does Helicobacter pylori cause gastric cancer through connexins: An opinion review. World J Gastroenterol 2019; 25(35): 5220-5232
URL: https://www.wjgnet.com/1007-9327/full/v25/i35/5220.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i35.5220