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Copyright ©The Author(s) 2019.
World J Gastroenterol. Jul 14, 2019; 25(26): 3334-3343
Published online Jul 14, 2019. doi: 10.3748/wjg.v25.i26.3334
Table 1 Classification of choledochal cysts according to the Todani classification
Todani classification
Type ISolitary extrahepatic cyst
Type IIExtrahepatic supraduodenal diverticulum
Type IIIIntraduodenal cyst
Type IVBoth extrahepatic and intrahepatic cysts
Type VMultiple intrahepatic cysts
Table 2 Summary data for the five largest Western studies compared to the five largest Eastern studies, specifically investigating the presentation and management of choledochal cyst disease in the last 20 years
Western
Eastern
Aggregate
Moslim et al[6]Edil et al[2]Soares et al[11]Singham et al[12]Baison et al (unpublished data)Shi et al[8]She et al[9]Woon et al[10]He et al[25]Lee et al[24]Aggrega-te EastAggrega-te West
Single-center or multi-centerSingleSingleMultipleSingleSingleMultipleSingleSingleSingleMultiple3-Single2-Multi4-Single1-Multi
Total number679239470103108833221480832-80867-394
Adults78%79%66%73%100%84%0%100%-100%0-100%66%-100%
Study period1984 - 20141976-20061972-20141985-20021998-20181980-20001978-20081991-20051968-20131990-20071968-20131972-2018
APBJ--8% (cancer patients only)-57.3%93.4%--81.2%71.4%71.4%-93.4%8%-57.3%
Female:Male ratio4:019:013.2:14.2:14.7:13.7:12.6:13.5:13.7:13.8:12.6:1-3.8:13.2:1-9:1
Age (yr)46 (55.6-34.3)-45 (SD 15.2)-44.53 (18-74)27.8 (3-68)4 (0-16)41 (18-74)36.2 (1-78)42 (18-82)4-4244-46
Symp-tomatic72%-84.5%-83%--91%98%88%88%-91%72%-85%
Presen-tationAbdom-inal pain only51%91%61%88%44%57%47%91%78%75%47%-91%44%-91%
Pancrea-titis (recurr-ent)-31%19%-9%-22%-13%-13%-22%9%-31%
Choleli-thiasis-58%--8%---22%-22 --8%-58%
Jaundice15%34%19%39%6%71%42%41%25%21%21%-71%6%-39%
Cholecy-stitis----6%---28%-28% --6 --
Cholan-gitis (recurr-ent)----3%56%----56% --3 --
Choled-ocholith-iasis----3%---29%28%28%-29%3 --
Weight loss, Bloating-8%--2%------ - -2%-8%
Other-2%--2%--9%--9% --2%-2%
Acute pancrea-titis13%---1%------ - -1%-13%
Fever/ chills-26%-39%-57%-34%19%-19%-57%26%-39%
Nausea/vomiting-47%-63%--31%38%--31%-38%47%-63%
Abdom-inal mass------22%25%4%-4%-25%- - -
Classic triad------2%13%--2%-13%- - -
CC typeI73%67%70%33%71%69%68%84%65%68%65%-84%67%-73%
II1.5%7%5%6%3%-5%6%1.4%0.9%0.9%-6%3%-7%
III-4%2%2%5%0.9%3%-0.5%0.5%0.5%-3%2%-5%
IV13.4%19%18%55%18%22%19%6%25%30%6%-30%18%-19%
V12%2%4.9%4%4%5.60%5%3%8%0.7%0.7%-8%2%-12%
Prior cholec-ystec-tomy-38%32%-28%--3%31%7%3%-31%28%-38%
Surgery100%100%98.9%100%70%100%90%84%92%100%84%-100%70%-100%
Biliary Malig-nancyOn presen-tation7.5%5.4%3%7.8%7%17%0%3%5%10%0-17%3-8%
On follow-up/re-currence1.5%3.2%3.30%-0%10%0%0%2.3%3%0-10%0-3%
Overall mortal-ity7.5%7.6%4.50%0%2%9%0%0%6%4%0-9%0-8%