Copyright
©The Author(s) 2019.
World J Gastroenterol. Jun 28, 2019; 25(24): 3021-3029
Published online Jun 28, 2019. doi: 10.3748/wjg.v25.i24.3021
Published online Jun 28, 2019. doi: 10.3748/wjg.v25.i24.3021
Table 1 Summary of reports on computed tomography or magnetic resonance perfusion in esophageal cancer
Year | Patients | Biomarker candidate | Prediction of treatment outcome | |
Hayano et al[14] | 2007 | 31 | Baseline BF (CT perfusion) | High baseline BF associated with good response and OS after CRT (31) |
Makari et al[15] | 2007 | 46 | Baseline BF (CT perfusion) | High baseline BF associated with good response and OS after chemotherapy (36) and CRT (10) |
Djuric-Stefanovic et al[17] | 2015 | 40 | Post-therapeutic BF (CT perfusion) | Post-therapeutic BF < 30 mL/min/100 g can predict pCR with 100% of sensitivity and specificity |
Lei et al[13] | 2015 | 25 | Baseline Ktrans (MR perfusion) | Ktrans was significantly different between CR and non-CR after CRT |
Sun et al[12] | 2018 | 59 | Change of Ktrans (MR perfusion) | Change in Ktrans was the best parameter to assess treatment response |
Table 2 Summary of reports on diffusion-weighted imaging in esophageal cancer
Year | Patients | Biomarker candidate | Prediction of treatment outcome | |
Aoyagi et al[33] | 2011 | 80 | Baseline ADC | High baseline ADC associated with favorable survival after CRT |
Imanishi et al[36] | 2013 | 27 | Early change of ADC, post-CRT ADC | Increase of ADC/high post-CRT ADC associated with good response to CRT |
De Cobelli et al[35] | 2013 | 32 | Baseline ADC | High baseline ADC associated with poor response to CRT |
Van Rossum et al[39] | 2015 | 20 | Early change of ADC | Increase of ADC associated with good response to CRT |
Wang et al[37] | 2016 | 38 | Early change of ADC, post-CRT ADC | Increase of ADC/high post-CRT ADC associated with good response to CRT |
Li et al[38] | 2017 | 28 | Early change of ADC, post-CRT ADC | Increase of ADC/high post-CRT ADC associated with good response to CRT |
Cong et al[34] | 2019 | 52 | Baseline ADC | High baseline ADC associated with good response to RT |
- Citation: Hayano K, Ohira G, Hirata A, Aoyagi T, Imanishi S, Tochigi T, Hanaoka T, Shuto K, Matsubara H. Imaging biomarkers for the treatment of esophageal cancer. World J Gastroenterol 2019; 25(24): 3021-3029
- URL: https://www.wjgnet.com/1007-9327/full/v25/i24/3021.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i24.3021