Plasma microRNAs as potential new biomarkers for early detection of early gastric cancer

Table 1 Characteristics of the subjects included in this study

Characteristics	Discovery set (n = 30)			Validation set (n = 122)
	EGC	AGC	BG	EGC	AGC	Control-1	Control-2
Number	10	10	10	20	22	40	40
Age (yr) (mean ± SD)	53.4 ± 2.6	57.0 ± 7.5	51.4 ± 10.0	63.3 ± 10.1	55.6 ± 13.9	50.2 ± 10.3	56.1 ± 11.3
Gender
Male	6	6	5	9	12	20	22
Female	4	4	5	11	10	20	18
H. pylori						-	+
Pathology
HGIN	4			13
Intramucosal cancer	6			7
TNM
HGIN	4			13
T1a	6			7
…
T4N2M0		2			2
T4N3M0		4			14
T4N3M1		4			6

EGC: Early gastric cancer; AGC: Advanced gastric cancer; BG: Benign gastritis; Control-1: Helicobacter pylori-negative gastritis; Control-2: Helicobacter pylori-positive atrophic gastritis; H. pylori: Helicobacter pylori; HGIN: High Grade Intraepithelial Neoplasia.