Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase

doi:10.3748/wjg.v24.i7.819

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Feb 21, 2018 (publication date) through Dec 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2018; 24(7): 819-832
Published online Feb 21, 2018. doi: 10.3748/wjg.v24.i7.819

Table 1 The primers used for RT-PCR analysis

Primer (Mouse)	Sequence (5’-3’)
GAPDH F	AAATGGTGAAGGTCGGTGTGAAC
GAPDH R	CAACAATCTCCACTTTGCCACTG
α-SMA F	GACAATGGCTCTGGGCTCTGTA
α-SMA R	TTTGGCCCATTCCAACCATTA
COL1A1 F	GACATGTTCAGCTTTGTGGACCTC
COL1A1 R	GGGACCCTTAGGCCATTGTGTA

α-SMA: Alpha-smooth muscle actin; COL1A1: Collagen type 1 alpha 1.

Citation: Li Z, Ding Q, Ling LP, Wu Y, Meng DX, Li X, Zhang CQ. Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase. World J Gastroenterol 2018; 24(7): 819-832
URL: https://www.wjgnet.com/1007-9327/full/v24/i7/819.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i7.819