Neonatal rhesus monkeys as an animal model for rotavirus infection

Table 1 Diarrhea scores of the neonatal rhesus monkeys from 1 d post infection to 4 d post infection

Dose (PFUs)	Monkey ID	Diarrhea score1				Mean diarrhea score2				Percentage with diarrhea (%)3
		1 dpi	2 dpi	3 dpi	4 dpi	1 dpi	2 dpi	3 dpi	4 dpi	1 dpi	2 dpi	3 dpi	4 dpi
108	17020	4	4	3	2
	17011	3	4	4	-	3.67	4	3.5	-	100	100	100	-
	17015	4	4	-	-
107	17018	2	0	0	1
	17003	2	0	0	1	2.67	0.67	0.33	1	100	33.3	0	0
	17001	4	2	1	1
106	17008	0	2	0	1
	17012	0	1	2	0	0	1.33	1	0.33	0	33.3	33.3	0
	17016	0	1	1	0
0	17006	0	0	0	0
	17002	0	0	0	-	0.33	0	0	-	0	0	0	-
	17004	1	0	-	-

¹0 was considered failure to collect feces by gently pressing the abdomen of the neonatal rhesus monkeys (we collected feces from the bottom of the incubator);

²Mean diarrhea score: The sum of all diarrhea or not-diarrhea scores/n (n = the number of total samples);

³Percentage with diarrhea (%): The number of diarrhea monkeys/the total number of monkeys in this group. 1 was considered no diarrhea (brown hard feces); 2 was considered common diarrhea (soft feces); 3 was considered severe diarrhea(loose feces); 4 was considered very severe diarrhea (watery feces). -: The monkey was sacrificed for histological analysis.