Temporal clinical, proteomic, histological and cellular immune responses of dextran sulfate sodium-induced acute colitis

Table 1 Disease activity index scoring

Score	Weight loss	Stool consistency	Bleeding
0	None	Normal	No bleeding
1	1%-5%	-	-
2	5%-10%	Loose stools	Slight bleeding
3	10%-15%	-	-
4	More than 15%	Watery diarrhea	Gross bleeding

Table 2 Histological scoring

Feature graded	Grade	Description
Inflammation	0	None
	1	Slight
	2	Moderate
	3	Severe
Extent	0	None
	1	Mucosa
	2	Mucosa and submucosa
	3	Transmural
Regeneration	4	No tissue repair
	3	Surface epithelium not intact
	2	Regeneration with crypt depletion
	1	Almost complete regeneration
	0	Complete regeneration or normal tissue
Crypt damage	0	None
	1	Basal 1/3 damaged
	2	Basal 2/3 damaged
	3	Only surface epithelium intact
	4	Entire crypt and epithelium lost
Percent involvement	1	1%-25%
	2	26%-50%
	3	51%-75%
	4	76%-100%