Association between acute pancreatitis and small intestinal bacterial overgrowth assessed by hydrogen breath test

Table 1 Association between acute pancreatitis of different severity grades and small intestinal bacterial overgrowth

Disease classification	Total (n)	SIBO positive	SIBO negative	χ2	P value
Mild	95	8	87	10.494	0.005
Moderate to severe	86	22	64
Severe	27	7	20

SIBO: Small intestinal bacterial overgrowth.

Table 2 Comparison of small intestinal bacterial hydrogen production in patients with acute pancreatitis in the early and late stages

Time	Hydrogen production (ppm)	T	P value
Early stage (within 72 h)	51.72 ± 1.63	4.734	0.000
Late stage (within 7 d)	32.7 ± 0.69

Table 3 Correlation between small intestinal bacterial overgrowth and complications of acute pancreatitis

Complication	SIBO positive group(n = 37)	SIBO negative group(n = 171)	χ2	P value
Organ failure
Yes	19	44	9.456	0.002
No	18	127
SIRS
Yes	22	113	0.586	0.444
No	15	58
Infection
Yes	9	42	0.001	0.976
No	28	129
Local complications
Yes	12	73	1.324	0.250
No	25	98

SIBO: Small intestinal bacterial overgrowth.