Post-colonoscopy colorectal cancer rate in the era of high-definition colonoscopy

Table 1 Baseline variables in the post-colonoscopy colorectal cancer and non- post-colonoscopy colorectal cancer group n (%)

	PCCRC	Non-PCCRC	P value
Patients	11	840
Gender			NS
Male	6 (54.5)	485 (57.7)
Female	5 (45.5)	355 (42.3)
Age (yr)			NS
mean ± SD	70 ± 10	68 ± 11
Range	53-82	29-92
Tumors Size (mm)	11	881	0.002
Mean ± SD	19 ± 13	39 ± 20
Range	4-50	4-110
Location			NS
Proximal	6 (54.5)	283 (32.1)
Distal	5 (45.5)	598 (67.9)
Depth			0.010
T1	7 (63.6)	224 (25.4)
T2-4	4 (36.4)	657 (74.6)
Shape1			0.020
Polypoid	1 (14.3)	136 (61.0)
Non-polypoid	6 (85.7)	87 (39.0)
UICC stage			0.033
Stage I,II	10 (90.9)	526 (59.7)
Stage III, IV	1 (9.1)	355 (40.3)

¹Shape of early CRC (T1 stage). PCCRC: Post-colonoscopy colorectal cancer; NS: Not significant; SD: Standard deviation; UICC: Union for International Cancer Control.

Table 2 Data for the 11 patients with post-colonoscopy colorectal cancer

No	Sex	Age(yr)	Interval (mo)	Tumor shape	Size (mm)	Depth	Location	Initial CS	Possible reason
1	M	79	7	IIc	5	T1a	T	Multiple polyps	Missed/new
2	M	76	14	IIa (LST-NG)	15	T1a	S	Multiple polyps	Missed/new
3	M	82	17	IIa (LST-NG)	25	T1a	T	No polyps	Missed/new
4	F	65	22	IIa (LST-NG)	20	T1a	A	Multiple polyps	Missed/new
5	M	59	26	Is	12	T1a	R	Two polyps	Missed/new
6	F	73	11	IIa	10	T1b	T	Piecemeal EMR	Incomplete resection
7	M	79	15	Is + IIc	4	T1b	S	Multiple polyps	Missed/new
8	F	70	9	Type 2	30	T3	C	No polyps	Inadequate examination
9	F	53	12	Type 2	17	T3	S (SDJ)	No polyps	Missed/new
10	F	77	12	Type 2	50	T3	RS	One polyp	Missed/new
11	M	66	10	Type 2	20	T4	C	Two polyps	Missed/new

Multiple, n ≥ 3. PCCRC: Post-colonoscopy CRC; CS: Colonoscopy; LST-NG: Laterally spreading tumor non-granular type; SDJ: Sigmoid-descending junction; EMR: Endoscopic mucosal resection.