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©The Author(s) 2017.
World J Gastroenterol. Sep 21, 2017; 23(35): 6437-6447
Published online Sep 21, 2017. doi: 10.3748/wjg.v23.i35.6437
Published online Sep 21, 2017. doi: 10.3748/wjg.v23.i35.6437
Table 1 Baseline characteristics (n = 115 patients, 127 nodules) n (%)
Characteristics | Values |
Age | |
Median (range) | 73 (49-92) |
Sex | |
Male/Female | 88 (76.5)/27 (23.5) |
Etiology | |
Hepatitis B/C/B + C | 13 (11.3)/85 (73.9)/2 (1.7) |
Alcohol | 10 (8.7) |
NASH | 2 (1.7) |
PBC | 3 (2.6) |
Child-Pugh class | |
A/B | 99 (86.1)/16 (13.9) |
Location of target nodules | |
Anterior segment | 39 (30.7) |
Posterior segment | 37 (29.1) |
Medial segment | 27 (21.3) |
Lateral segment | 24 (18.9) |
Size of target nodules (mm)1 | 14.00 ± 10.30 (5.0-56.7) |
Chemotherapeutic drug | |
Cisplatin/Epirubicin | 87 (68.5)/40 (31.5) |
Table 2 Evaluation of efficacy 6 mo after transcatheter arterial chemoembolization according to the modified response evaluation criteria in solid tumors criteria
CR | PR | SD | PD | Total | |
All nodules | 81 | 26 | 13 | 7 | 127 |
(63.8) | (20.5) | (10.2) | (5.5) | ||
Anterior segment | 26 | 7 | 5 | 1 | 39 |
Posterior segment | 22 | 8 | 3 | 4 | 37 |
Medial segment | 14 | 8 | 4 | 1 | 27 |
Lateral segment | 19 | 3 | 1 | 1 | 24 |
Patient with Child-Pugh grade A | 56 | 17 | 10 | 3 | 86 |
(65.1) | (19.8) | (11.6) | (3.5) | ||
Anterior segment | 19 | 5 | 5 | 1 | 30 |
Posterior segment | 14 | 5 | 1 | 1 | 21 |
Medial segment | 9 | 6 | 3 | 0 | 18 |
Lateral segment | 14 | 1 | 1 | 1 | 17 |
Patients with Child-Pugh grade B | 25 | 9 | 3 | 4 | 41 |
(61.0) | (22.0) | (7.3) | (9.7) | ||
Anterior segment | 7 | 2 | 0 | 0 | 9 |
Posterior segment | 8 | 3 | 2 | 3 | 16 |
Medial segment | 5 | 2 | 1 | 1 | 9 |
Lateral segment | 5 | 2 | 0 | 0 | 7 |
Table 3 Hepatocellular carcinoma location coefficient in the complete response and non-complete response groups
Non-CR group | CR group | P value | |
All lobes | 0.63 | 0.8 | < 0.001 |
Right lobe | 0.68 | 0.81 | < 0.05 |
Medial segment | 0.49 | 0.8 | < 0.01 |
Lateral segment | 0.73 | 0.74 | > 0.05 |
Patients with Child-Pugh grade A | |||
All lobes | 0.62 | 0.82 | < 0.001 |
Right lobe | 0.59 | 0.71 | < 0.01 |
Medial segment | 0.49 | 0.81 | < 0.05 |
Lateral segment | 0.65 | 0.67 | > 0.05 |
Patients with Child-Pugh grade B | |||
All lobes | 0.73 | 0.75 | > 0.05 |
Right lobe | 0.84 | 0.79 | > 0.05 |
Medial segment | 0.43 | 0.69 | > 0.05 |
Lateral segment | 0.72 | 0.69 | > 0.05 |
- Citation: Miki I, Murata S, Uchiyama F, Yasui D, Ueda T, Sugihara F, Saito H, Yamaguchi H, Murakami R, Kawamoto C, Uchida E, Kumita SI. Evaluation of the relationship between hepatocellular carcinoma location and transarterial chemoembolization efficacy. World J Gastroenterol 2017; 23(35): 6437-6447
- URL: https://www.wjgnet.com/1007-9327/full/v23/i35/6437.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i35.6437