Review
Copyright ©The Author(s) 2017.
World J Gastroenterol. Jul 14, 2017; 23(26): 4675-4688
Published online Jul 14, 2017. doi: 10.3748/wjg.v23.i26.4675
Table 1 Baseline cancer biomarkers shown in preliminary analysis of the Screening Patients for Efficient Clinical Trial Access in advanced colorectal cancer’s molecular screening platform
KRAS WTKRAS exon 2 mutatedKRAS exon 3 and exon 4 mutated
151 of 284 patients (53%)114 patients in exon 2 (40%)8 patients in exon 3 (3%), 11 patients in exon 4 (4%)
NRAS mutated (KRAS WT)PI3KCABRAF
14 patients (4.9%); 6 patients in exon 2 and 8 patients in exon 341 patients (15%), 13 in exon 20 and 28 in exon 918 patients in exon 15 (7%)