Mitochondrial carnitine palmitoyl transferase-II inactivity aggravates lipid accumulation in rat hepatocarcinogenesis

doi:10.3748/wjg.v23.i2.256

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2017; 23(2): 256-264
Published online Jan 14, 2017. doi: 10.3748/wjg.v23.i2.256

Table 1 Biochemical alterations and liver cell injury in different rats

Group	n	Tch (mmol/L)	TG (mmol/L)	ALT (IU)	AST (IU)
Control	10	1.88 ± 0.42	1.09 ± 0.42	6.26 ± 2.76	8.15 ± 3.70
Fatty liver	39	3.36 ± 1.43^a	1.69 ± 1.12^a	27.48 ± 21.64^a	22.87 ± 17.51^a
Degeneration	17	6.26 ± 1.79^a	4.51 ± 3.10^a	54.45 ± 33.82^a	35.09 ± 14.72^a
Precancerous	15	4.84 ± 1.37^a	4.68 ± 2.20^a	48.83 ± 29.30^a	50.38 ± 22.65^a
Cancerous	10	5.10 ± 1.18^a	3.10 ± 1.76^a	32.97 ± 21.34^a	31.41 ± 16.13^a

^aP < 0.05 vs control group. Tch: Total cholesterol; TG: Triglyceride; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.

Citation: Gu JJ, Yao M, Yang J, Cai Y, Zheng WJ, Wang L, Yao DB, Yao DF. Mitochondrial carnitine palmitoyl transferase-II inactivity aggravates lipid accumulation in rat hepatocarcinogenesis. World J Gastroenterol 2017; 23(2): 256-264
URL: https://www.wjgnet.com/1007-9327/full/v23/i2/256.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i2.256