Correlation of endoscopic disease severity with pediatric ulcerative colitis activity index score in children and young adults with ulcerative colitis

Table 1 Descriptive information regarding the dataset (n = 99)

Characteristic	n (%)
Gender
Male	47 (47)
Female	52 (53)
Ulcerative colitis (UC) duration - scope
New onset	1 (1)
< 1 yr	16 (16)
1-3 yr	30 (30)
3-5 yr	16 (16)
> 5 yr	36 (36)
Indication for procedure
Suspicion of UC	1 (1)
Active symptoms	61 (62)
Consideration of Medication change	10 (10)
Assessment of Medication efficacy	13 (14)
Cancer screening	14 (14)
Paris classification
E1 Proctitis	1 (1)
E2 Left-sided	20 (20)
E3 Extensive	5 (5)
E4 Pancolitis	73 (74)
Medications at time of colonoscopy
5-aminosalicylic acid (5 ASA)	67 (68)
Steroids	30 (30)
Mercaptopurine/methotrexate	33 (33)
Infliximab/adalimumab	12 (12)
Antibiotics	10 (10)
Five ASA Enema	5 (5)
Hydrocortisone Enema	10 (10)
Methotrexate	1 (1)
Tacrolimus	3 (3)
VSL 3 probiotic	10 (10)

Table 2 Inter-observer agreement in grading rectal disease severity (Mayo scores) between reviewers

Reviewer AB	Reviewer PR
	0	1	2	3	Unknown	Total
0	22	4	1	0	0	27
1	1	22	12	1	0	36
2	0	2	8	4	0	14
3	0	0	1	3	0	4
Unknown	0	0	0	0	18	18
Total	23	28	22	8	18	99

Table 3 Inter-observer agreement in grading sigmoid disease severity (Mayo score) between reviewers

Reviewer AB	Reviewer PR
	0	1	2	3	Unknown	Total
0	22	5	0	0	0	27
1	2	22	12	4	0	40
2	0	3	9	7	0	19
3	0	0	5	3	0	8
Unknown	0	0	0	0	5	5
Total	24	30	26	14	5	99

Table 4 Pediatric ulcerative colitis activity index data by component

Characteristic	mean ± SD or n (%)
Age at time of colonoscopy (yr)	15.7 (4.1)
Days between colonoscopy and PUCAI score	14.8 (10.6)
Method of PUCAI collection
Prospectively entered at time of clinic visit	27 (27)
Calculated from medical record	72 (73)
Abdominal pain
No pain	52 (53)
Present but ignored	36 (36)
Cannot be ignored	11 (11)
Rectal bleeding
None	49 (49)
Small amount, < 50%	20 (20)
Small amount, most	27 (27)
Large amount	3 (3)
Consistency
Formed	57 (58)
Partially formed	35 (35)
Completely unformed	7 (7)
Number of stools
0-2	61 (62)
3-5	21 (21)
6-8	11 (11)
> 8	6 (6)
Nocturnal stools	18 (18)
Activity limitation
No limitation	62 (63)
Occasional limitation	29 (29)
Severe restriction	8 (8)
Overall activity
Remission, 0-9	33 (33)
Mild, 10-34	39 (39)
Moderate, 35-64	23 (23)
Severe, > 64	4 (4)

PUCAI: Pediatric ulcerative colitis activity index.