Copyright
©The Author(s) 2017.
World J Gastroenterol. May 14, 2017; 23(18): 3295-3300
Published online May 14, 2017. doi: 10.3748/wjg.v23.i18.3295
Published online May 14, 2017. doi: 10.3748/wjg.v23.i18.3295
Table 1 Patient characteristics n (%)
Characteristics | Value (n = 37) |
Female sex | 22 (60) |
Age, median (range) | 68 (48-81) |
Enlargement of the pancreas | |
Diffuse | 21 (57) |
Segmental | 16 (43) |
Irregular narrowing of the MPD by ERP | |
Diffuse | 23 (62) |
Segmental | 7 (19) |
NA | 7 (19) |
Serum IgG4 (mg/dL), median (range) | 462 (3-2870) |
Table 2 Impact of corticosteroid administration on ultrasonographic findings in submandibular glands
Pre-Tx(n = 18) | Post-Tx(n = 18) | P value | |
Thickness of SGs (mm), mean ± SD | 16.1 ± 4.2 | 13.5 ± 3.5 | 0.002 |
Echogenicity of SGs | |||
Homogenous | 2 | 3 | |
Multiple hypoechoic lesions | 16 | 2 | |
Obscured hypoechoic lesions | 13 |
Table 3 Difference in sensitivity among diagnostic methods for sialadenitis n (%)
Examined cases | Positive examination | |
SG swelling on physical examination | 33 | 15 (46) |
Ga accumulation in SGs by scintigraphy | 25 | 7 (28) |
Increased thickness in SGs by US (≥ 15 mm) | 37 | 18 (49) |
Multiple hypoechoic lesions in SGs by US | 37 | 31 (84) |
Multiple hypoechoic lesions in parotid glands by US | 36 | 5 (14) |
Table 4 Other organ involvement
n | |
Level 1 findings | |
IgG4-related SC | 4 |
Retroperitoneal fibrosis | 5 |
Level 2 findings | |
Enlarged salivary glands | 20 |
Sialadenitis by SGUS | 31 |
Renal involvement | 4 |
Final diagnosis of OOI | |
Level 1 | 8 |
Level 2 | 18 |
Level 2 by SGUS | 25 |
Table 5 Classification of primary diagnosis for type 1 autoimmune pancreatitis
Primary basis for diagnosis | Final diagnosis | Definitive diagnosis without OOI | Definitive diagnosis with OOI | Definitive diagnosis with SGUS |
Histology | 1 | 1 | ||
Typical imaging | 21 | 19 | 1 | 1 |
Indeterminate imaging | 8 | 8 | ||
Response to steroid | 7 | 6 | 1 |
- Citation: Takano S, Fukasawa M, Kadokura M, Shindo H, Takahashi E, Hirose S, Fukasawa Y, Kawakami S, Sato T, Enomoto N. Clinical significance of hypoechoic submandibular gland lesions in type 1 autoimmune pancreatitis. World J Gastroenterol 2017; 23(18): 3295-3300
- URL: https://www.wjgnet.com/1007-9327/full/v23/i18/3295.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i18.3295