Effects of Saccharomyces cerevisiae or boulardii yeasts on acute stress induced intestinal dysmotility

Table 1 Effects of stress on gut propagating contractile clusters

Parameter	Tissue	Unstressed	Stressed	P value (t test)
Velocity (mm/s)	Jejunum	2.635 ± 0.316 (17)	1.644 ± 0.238 (17)	< 0.001
	Colon	0.864 ± 0.183 (17)	1.432 ± 0.329 (17)	< 0.001
Frequency (Hz)	Jejunum	0.032 ± 0.008 (17)	0.016 ± 0.005 (17)	< 0.001
	Colon	0.005 ± 0.001 (17)	0.007 ± 0.001 (17)	0.008
Peak amplitude (mm)	Jejunum	0.437 ± 0.020 (17)	0.790 ± 0.015 (17)	< 0.001
	Colon	0.640 ± 0.118 (17)	0.645 ± 0.101 (17)	0.902

Table 2 Effects of Saccharomyces boulardii on propagating contractile clusters in unstressed gut

Parameter	Tissue	Unstressed	+boulardii	P value (t test)
Velocity (mm/s)	Jejunum	2.556 ± 0.299 (32)	3.229 ± 0.620 (32)	< 0.001
	Colon	0.865 ± 0.148 (27)	0.633 ± 0.225 (27)	< 0.001
Frequency (Hz)	Jejunum	0.030 ± 0.018 (33)	0.035 ± 0.025 (33)	0.030
	Colon	0.009 ± 0.004 (27)	0.007 ± 0.003 (27)	0.005
Peak amplitude (mm)	Jejunum	0.587 ± 0.241 (33)	0.623 ± 0.291 (33)	0.290
	Colon	0.621 ± 0.190 (27)	0.543 ± 0.179 (27)	0.005

Table 3 Effects of Saccharomyces boulardii on propagating contractile clusters in stressed gut

Parameter	Tissue	Stressed	+boulardii	P value (t test)
Velocity (mm/s)	Jejunum	1.833 ± 0.688 (26)	2.627 ± 0.664 (26)	< 0.001
	Colon	1.516 ± 0.263 (24)	1.036 ± 0.210 (24)	< 0.001
Frequency (Hz)	Jejunum	0.019 ± 0.013 (26)	0.032 ± 0.024 (26)	0.005
	Colon	0.010 ± 0.003 (24)	0.007 ± 0.003 (24)	0.001
Peak amplitude (mm)	Jejunum	0.692 ± 0.215 (26)	0.698 ± 0.212 (26)	0.705
	Colon	0.719 ± 0.249 (24)	0.657 ± 0.152 (24)	0.259

Table 4 Effects of Saccharomyces cerevisiae on propagating contractile clusters in unstressed gut

Parameter	Tissue	Unstressed	+cerevisiae	P value (t test)
Velocity (mm/s)	Jejunum	2.779 ± 0.499 (43)	3.017 ± 0.457 (43)	0.017
	Colon	0.788 ± 0.212 (23)	0.858 ± 0.257 (23)	0.161
Frequency (Hz)	Jejunum	0.027 ± 0.012 (43)	0.031 ± 0.008 (43)	0.003
	Colon	0.0051 ± 0.001 (23)	0.0054 ± 0.001 (23)	0.462
Peak amplitude (mm)	Jejunum	0.409 ± 0.111 (43)	0.438 ± 0.098 (43)	0.242
	Colon	0.559 ± 0.176 (23)	0.508 ± 0.15 (23)	0.164

Table 5 Effects of Saccharomyces cerevisiae on propagating contractile clusters in stressed gut

Parameter	Tissue	Stressed	+cerevisiae	P value (t test)
Velocity (mm/s)	Jejunum	1.763 ± 0.397 (23)	2.017 ± 0.480 (23)	0.0031
	Colon	1.647 ± 0.187 (23)	1.038 ± 0.222 (23)	< 0.001
Frequency (Hz)	Jejunum	0.016 ± 0.009 (23)	0.027 ± 0.007 (23)	< 0.001
	Colon	0.008 ± 0.002 (23)	0.008 ± 0.003 (23)	0.994
Peak amplitude (mm)	Jejunum	0.761 ± 0.316 (23)	0.559 ± 0.148 (23)	0.013
	Colon	0.640 ± 0.101 (23)	0.597 ± 0.103 (23)	0.190

Table 6 Effects of Saccharomyces boulardii supernatant on propagating contractile clusters in stressed gut

Parameter	Tissue	Stressed	+boulardii Snt	P value (t test)
Velocity (mm/s)	Jejunum	1.97 ± 0.39 (6)	2.585 ± 0.468 (6)	< 0.001
	Colon	1.588 ± 0.194 (6)	1.11 ± 0.383 (6)	0.038
Frequency (Hz)	Jejunum	0.020 ± 0.014 (6)	0.044 ± 0.027 (6)	0.067
	Colon	0.010 ± 0.001 (6)	0.007 ± 0.003 (6)	0.024
Peak amplitude (mm)	Jejunum	0.75 ± 0.285 (6)	0.737 ± 0.187 (6)	0.93
	Colon	0.65 ± 0.188 (6)	0.701 ± 0.09 (6)	0.59

Table 7 Effects of Saccharomyces cerevisiae supernatant on propagating contractile clusters in stressed gut

		Stressed	+cerevisiae Snt	P value (t test)
Velocity (mm/s)	Jejunum	0.713 ± 0.109 (6)	0.466 ± 0.122 (6)	0.97
	Colon	1.639 ± 0.18 (6)	1.018 ± 0.245 (6)	0.002
Frequency (Hz)	Jejunum	0.018 ± 0.004 (6)	0.029 ± 0.004 (6)	0.003
	Colon	0.0076 ± 0.001 (6)	0.0074 ± 0.001 (6)	0.83
Peak amplitude (mm)	Jejunum	0.713 ± 0.109 (6)	0.466 ± 0.122 (6)	0.0016
	Colon	0.741 ± 0.177 (6)	0.510 ± 0.202 (6)	0.10