Pregnancy and inflammatory bowel disease: Do we provide enough patient education? A British study of 1324 women

Table 1 Patient demographics n (%)

Patient demographics	Value
Age (yr)	Mean 33.5 (18-45)
Ethnicity
White	1258 (95.0)
Asian	34 (2.6)
Black	6 (0.5)
Other	26 (1.9)
Highest educational achievement
Secondary school	157 (11.9)
Apprenticeship/guild/NVQ	386 (29.1)
Bachelor	577 (43.6)
Master/PhD	204 (15.4)
Employment status
Full time employment	697 (52.6)
Part time employment	337 (25.5)
Full time education	102 (7.7)
Unemployed	80 (6.0)
House person	108 (8.2)
Relationship status
Single	259 (19.6)
Separated/divorced	44 (3.3)
Long term relationship/married/civil partnership	1009 (76.2)
Other	12 (0.9)
Same sex relationship
Yes	66 (5.0)
No	1250 (94.4)
Chose not to answer	8 (0.6)

Table 2 Disease and treatment characteristics n (%)

Characteristics	Value
Diagnosis
CD	776 (58.6)
UC	496 (37.5)
IBD-U	48 (3.6)
Unknown	4 (0.3)
Age at diagnosis	Mean 25 yr
	Median 24 yr
Duration of disease	Mean 8.5 yr
	Median 7 yr
Hospital admissions
Yes	923 (69.3)
No	401 (30.3)
	Median 2 admissions
Bowel resection surgery
Yes	437 (32.3)
No	897 (67.7)
	Median 2 resections
5-ASA medication
Current	615 (46.4)
Previous	521 (39.4)
Never	188 (14.2)
Corticosteroids
Current	175 (13.2)
Previous	948 (71.6)
Never	201 (15.2)
Immunomodulators
Current	597 (45.1)
Previous	368 (27.7)
Never	359 (27.2)
Anti-TNF agents
Current	280 (21.1)
Previous	196 (14.8)
Never	848 (64.1)

CD: Crohn’s disease; IBD-U: Inflammatory bowel disease-unclassified; UC: Ulcerative colitis; TNF: Tumor necrosis factor.

Table 3 Patient demographics, disease characteristics and impact of speaking to healthcare professionals on Crohn’s and colitis pregnancy knowledge score

Factor	Groups	CCPKnow score	Significance
Age	N/A	Pearson correlation -0.131	P < 0.001
Age at diagnosis	N/A	Pearson correlation -0.212	P < 0.001
Ethnicity	White	7.32	P = 0.773
	Mixed	8.00
	Asian	6.59
	Black	6.33
	Other	7.43
Education	Secondary school	5.99	P < 0.001
	NVQ/diploma	6.08
	Bachelors degree	8.02
	Masters/PhD	8.67
Relationship status	Single	6.26	P < 0.001
	Separated/divorced	6.82
	Long term relationship	7.60
	Not stated	7.67
Employment status	Full-time	7.18	P = 0.30
	Part-time	7.73
	Full-time education	7.46
	Unemployed	6.12
	House person	7.59
Same-sex relationship	Yes	6.71	P = 0.451
	No	7.35
	Chose not to answer	6.63
Diagnosis	CD	7.51	P = 0.051
	UC	6.97
	IBD-U	7.85
	Unknown	4.25
Children	Group 1	7.71	P = 0.007
	Group 2	7.05
Partner with IBD	Yes	8.64	P = 0.241
	No	7.30
Hospital admissions	Admission	7.59	P < 0.001
	None	6.66
Resection surgery	Yes	7.71	P = 0.018
	No	7.12
Current 5-ASA prescription	Yes	7.06	P = 0.048
	No	7.53
Current immunomodulatory	Yes	7.67	P = 0.006
prescription	No	7.02
Current anti-TNF	Yes	8.30	P < 0.0001
prescription	No	7.05
Spoken to HCP	Yes	8.75	P < 0.001
	No	5.82
Spoken to GP	Yes	8.44	P < 0.001
	No	6.98
Spoken to gastroenterologist	Yes	9.18	P < 0.001
	No	6.25
Spoken to IBD nurse	Yes	9.27	P < 0.001
	No	6.83

CD: Crohn’s disease; IBD-U: Inflammatory bowel disease-unclassified; UC: Ulcerative colitis.

Table 4 Multiple linear regression analysis

Factors	Beta-coefficient	Significance
Current 5-ASA (yes/no)	-0.490	P = 0.603
Current immunomodulators (yes/no)	-0.380	P = 0.663
Current biologics (yes/no)	0.111	P = 0.201
Educational achievement (university/no university)	0.292	P = 0.001
Work status (employed/unemployed)	-0.075	P = 0.369
Martial status (relationship/single)	0.120	P = 0.147
Child status (group 1/group 2)	-0.142	P = 0.157
Diagnosis (CD/UC)	0.090	P = 0.336
Surgery (yes/no)	-0.084	P = 0.426
Hospital admission (yes/no)	0.038	P = 0.676
Spoken to HCP (yes/no)	-0.317	P < 0.0001
Age	-0.211	P = 0.053
Age at diagnosis	-0.274	P = 0.003