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©The Author(s) 2016.
World J Gastroenterol. Sep 28, 2016; 22(36): 8103-8111
Published online Sep 28, 2016. doi: 10.3748/wjg.v22.i36.8103
Published online Sep 28, 2016. doi: 10.3748/wjg.v22.i36.8103
Table 1 Asia-Pacific Colorectal Screening scoring system (adapted from Wang et al[53])
Risk factor | Criterion | Point |
Age (yr) | < 50 | 0 |
50-69 | 1 | |
≥ 70 | 2 | |
Gender | Female | 0 |
Male | 1 | |
Immediate family member with colorectal cancer | No | 0 |
Yes | 1 | |
Smoking status | No smoking history | 0 |
Current or former smoker | 1 |
Table 2 Risk score for advanced neoplasia (adapted from Segnan et al[11])
Risk factor | Category | Point |
Age (yr) | 40-49 | 0 |
50-54 | 1 | |
55-59 | 2 | |
60-66 | 3 | |
> 66 | 3 | |
Sex | Female | 0 |
Male | 2 | |
Family history | None | 0 |
1 first-degree relative ≥ 60 years old | 1 | |
1 first-degree relative < 60 years old | 2 | |
2 first-degree relatives | 2 | |
Smoking, pack years | None | 0 |
< 10 | 0 | |
10-19 | 1 | |
≥ 20 | 1 | |
Body mass index (kg/m2) | < 25 | 0 |
25-29 | 0 | |
≥ 30 | 1 - Female | |
0 - Male |
Table 3 Comparison of non-advanced adenoma and colorectal neoplasia in the target and control groups
Target group (n = 726) | Control group (n = 774) | OR, 95%CI (P value)1 | |
Adenoma, n | 346 | 270 | 1.2, 0.9-1.5 |
(%, 95%CI) | (48%, 44%-51%) | (35%, 32%-38%) | (0.18) |
Advanced adenoma, n | 131 | 66 | 1.8, 1.2-2.5 |
(%, 95%CI) | (18%, 15%-21%) | (9%, 7%-11%) | (< 0.01) |
Cancer, n | 11 | 11 | 0.7, 0.3-1.6 |
(%, 95%CI) | (2%, 1%-3%) | (1%, 1%-3%) | (0.35) |
Table 4 Prevalence of non-advanced adenoma and colorectal neoplasia within the target group
Combination of DM2 and SCORE ≥ 10 (n = 157) | SCORE ≥ 10 (n = 413) | DM2 (n = 156) | P value1 | |
Adenoma, n | 69 | 211 | 66 | 0.33 |
(%, 95%CI) | (44%, 36%-52%) | (51%, 46%-56%) | (42%, 34%-50%) | |
Advanced adenoma, n | 25 | 89 | 17 | < 0.05 |
(%, 95%CI) | (16%, 11%-23%) | (22%, 18%-26%) | (11%, 6%-17%) | |
Cancer, n | 3 | 5 | 3 | 0.56 |
(%, 95%CI) | (2%, 0%-5%) | (1%, 0%-3%) | (2%, 0%-6%) |
- Citation: Suchanek S, Grega T, Ngo O, Vojtechova G, Majek O, Minarikova P, Brogyuk N, Bunganic B, Seifert B, Dusek L, Zavoral M. How significant is the association between metabolic syndrome and prevalence of colorectal neoplasia? World J Gastroenterol 2016; 22(36): 8103-8111
- URL: https://www.wjgnet.com/1007-9327/full/v22/i36/8103.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i36.8103