Global epidemiology of hepatitis C virus infection: An up-date of the distribution and circulation of hepatitis C virus genotypes

Table 1 Global anti-hepatitis C virus prevalence and number of infected individuals (all ages)

Continent	Anti- HCV prevalence (%)	Viraemic rate (%)	2013 population (millions)	Anti- HCV infected (millions)	Viraemic HCV infected (millions)
Africa	2.9	70.5	927.0	26.9	19.0
North Africa/Middle East	2.7	68.8	469.0	12.7	8.7
America	1.3	74.0	953.7	12.4	9.2
Asia	2.8	64.4	3985.0	111.6	71.9
Australasia	1.8	74.8	28.0	0.5	0.4
Europe	1.8	72.4	742.5	13.4	9.7
Total	2.5	67.0	7105.2	177.5	118.9

HCV: Hepatitis C virus.

Table 2 Regional estimates of hepatitis C virus seroprevalence and viraemia

Regions	Anti-HCV prevalence (%)	Viraemic rate (%)
Central Sub-Saharan Africa	6.0	68.5
EastSub-Saharan Africa	2.4	65.0
Southern Sub-Saharan Africa	0.9	69.0
WestSub-Saharan Africa	2.4	79.6
North Africa and Middle East	2.7	68.8
North America, High Income	1.2	75.7
Caribbean	1.5	70.0
Andean Latin America	1.2	70.0
Central Latin America	1.4	75.8
Southern Latin America	1.5	79.5
Tropical Latin America	1.6	80.2
Central Asia	5.8	48.7
East Asia	2.8	63.6
Pacific Asia, High-income	1.1	70.5
South Asia	2.5	78.5
Southeast Asia	1.6	60.5
Australasia	1.8	74.8
Europe, Central	1.3	76.6
Europe, Eastern	3.1	69.6
Europe, Western	0.9	71.0

HCV: Hepatitis C virus.

Table 3 Global prevalence of hepatitis C virus genotypes

Continents	G1 (%)	G2 (%)	G3 (%)	G4 (%)	G5 (%)	G6 (%)	Mixed
Africa	26.3	23.7	6.3	28.1	12.2	-	3.4
North Africa/Middle East	27.3	0.8	6.3	65.3	0.3	-	-
America	74.5	10.2	10.6	1.7	0.1	0.3	2.6
Asia	46.6	18.6	22.4	1.0	0.1	7.0	4.3
Australasia	55.0	6.5	36.0	1.2	-	1.3	-
Europe	64.4	5.5	25.5	3.7	0.1	0.1	0.7
Total (excludes Oceania)	49.1	11.0	17.9	16.8	2.0	1.4	1.8

Table 4 Regional estimates of hepatitis C virus genotypes

Regions	G1 (%)	G2 (%)	G3 (%)	G4 (%)	G5 (%)	G6 (%)	Mixed
Central Sub-Saharan Africa	12.3	4.0	0.8	82.9	-	-	-
East Sub-Saharan Africa	36.2	26.8	7.4	16.6	13.0	-	-
Southern Sub-Saharan Africa	31.4	1.2	12.6	12.4	35.7	-	6.7
West Sub-Saharan Africa	25.5	62.9	4.4	0.6	-	-	6.6
North Africa and Middle East	27.3	0.8	6.3	65.3	0.3	-	-
North America	66.3	13.1	15.7	4.3	-	0.6	-
Caribbean	83.0	7.2	2.1	0.6	-	0.1	7.0
Andean Latin America	86.0	2.0	10.0	-	-	-	2.0
Central Latin America	74.6	21.6	3.3	0.1	0.1	-	0.3
Southern Latin America	72.0	13.3	13.5	0.9	0.1	0.1	0.1
Tropical Latin America	64.8	4.6	30.2	0.2	0.1	-	0.1
Central Asia	70.4	8.6	19.6	-	-	-	1.4
East Asia	53.5	31.7	5.4	0.1	-	3.3	6.0
Pacific Asia, High-Income	58.7	39.7	0.4	0.1	-	0.5	0.6
South Asia	15.5	1.9	66.7	3.7	0.1	0.5	11.6
Southeast Asia	35.2	11.1	19.9	0.9	0.4	30.8	1.7
Australasia	55.0	6.5	36.0	1.2	-	1.3	-
Central Europe	70.0	3.2	21.0	4.9	-	0.1	0.8
Eastern Europe	68.1	4.3	26.6	0.5	-	-	0.5
Western Europe	55.1	8.9	29.0	5.8	0.2	0.1	0.8