Basic Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Aug 21, 2016; 22(31): 7111-7123
Published online Aug 21, 2016. doi: 10.3748/wjg.v22.i31.7111
Table 1 Inflammatory parameters in low dose 1% dextran sulfate sodium-induced colonic hypersensitivity model
WaterDSS
Histological score0.1 ± 0.14.0 ± 0.6b
MPO activity2.4 ± 0.34.0 ± 0.6
Table 2 Comparison of the carbamazepine, gabapentin or pregabalin efficacy on neonatal mother-separated and dextran sulfate sodium induced colonic hypersensitivity models
NMSDSS
CBZ10 mg/kg 9 ± 86 ± 18
30 mg/kg  5 ± 13-17 ± 15
GBP30 mg/kg  15 ± 32-45 ± 9
100 mg/kg-14 ± 37-56 ± 9
PGB10 mg/kg-16 ± 8-54 ± 7a
30 mg/kg-47 ± 13-66 ± 7b