Copyright
©The Author(s) 2016.
World J Gastroenterol. Jul 28, 2016; 22(28): 6559-6564
Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6559
Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6559
Table 1 World Health Organization criteria for SM (adapted from Valent et al 2001)[4]
| Major Criteria |
| Multifocal dense infiltrates of mast cells (> 15 mast cells in aggregates) at bone marrow biopsy and/or in sections of other extracutaneous organ(s) |
| Minor Criteria |
| > 25% of mast cells in bone marrow are atypical cells or spindle- shaped mast cells in infiltrates detected on sections of extracutaneous organ(s) |
| c-kit point mutation at codon 816 in the bone marrow or in another extracutaneous organ(s) |
| Mast cells in the bone marrow or in the another extracutaneous organ(s) expressing CD2 and/or CD25 with CD117 |
| Serum tryptase levels > 200 ng/mL |
- Citation: Martins C, Teixeira C, Ribeiro S, Trabulo D, Cardoso C, Mangualde J, Freire R, Gamito &, Alves AL, Cremers I, Alves C, Neves A, Oliveira AP. Systemic mastocytosis: A rare cause of non-cirrhotic portal hypertension. World J Gastroenterol 2016; 22(28): 6559-6564
- URL: https://www.wjgnet.com/1007-9327/full/v22/i28/6559.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i28.6559