Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells

doi:10.3748/wjg.v22.i20.4868

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 28, 2016; 22(20): 4868-4880
Published online May 28, 2016. doi: 10.3748/wjg.v22.i20.4868

Table 1 The changes of supernatant lactic acid concentrations after restraining the expression of hypoxia inducible factor-1 alpha (n = 3)

	TE13		Eca109
	TE13	TE13/siRNA	Eca109	Eca109/siRNA
A (19% O₂)	3.333 ± 0.833	1.933 ± 0.569^c	4.867 ± 0.551	1.367 ± 0.346^c
B (1% O₂)	6.433 ± 1.059^a	1.567 ± 0.416	8.067 ± 1.160^a	1.767 ± 1.242^a

^aP < 0.05, vs group A;

^cP < 0.05, vs non-interference group.

Citation: Zeng L, Zhou HY, Tang NN, Zhang WF, He GJ, Hao B, Feng YD, Zhu H. Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells. World J Gastroenterol 2016; 22(20): 4868-4880
URL: https://www.wjgnet.com/1007-9327/full/v22/i20/4868.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i20.4868