Expression of B7-H4 and hepatitis B virus X in hepatitis B virus-related hepatocellular carcinoma

Table 1 Expression and clinical significance of B7-H4 and hepatitis B virus X in hepatitis B virus-related hepatocellular carcinoma

	HBx		χ2/P	B7-H4		χ2/P
	No. of positive	No. of negative		No. of positive	No. of negative
Gender
Male	39	22	χ2 = 2.28	42	19	χ2 = 0.00
Female	10	12	P > 0.05	15	7	P > 0.05
Age (yr)
≤ 50	21	21	χ2 = 2.87	25	17	χ2 = 3.31
> 50	28	13	P > 0.05	32	9	P > 0.05
Tumor grade
I/II	36	24	χ2 = 0.08	39	21	χ2 = 1.36
III	13	10	P > 0.05	18	5	P > 0.05
TNM stage
I/II	15	23	χ2 = 11.09	23	15	χ2 = 2.16
III/IV	34	11	P < 0.01	34	11	P > 0.05

HBx: Hepatitis B virus X; HBV: Hepatitis B virus.

Table 2 Expression and clinical significance of B7-H4 in hepatitis B virus X-positive hepatitis B virus X-related hepatocellular carcinoma

	HBx-positive		P value
	B7-H4 expression scores	Case No.
Gender
Male	3.28 ± 1.65	39	> 0.05
Female	4.00 ± 1.56	10
Age (yr)
≤ 50	3.14 ± 1.62	21	> 0.05
> 50	3.64 ± 1.66	28
Tumor grade
I/II	3.33 ± 1.67	36	> 0.05
III	3.69 ± 1.60	13
TNM stage
I/II	4.13 ± 1.51	15	< 0.05
III/IV	3.12 ± 1.63	34

HBx: Hepatitis B virus X; HBV: Hepatitis B virus.