Retrospective Cohort Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Mar 28, 2016; 22(12): 3381-3391
Published online Mar 28, 2016. doi: 10.3748/wjg.v22.i12.3381
Table 1 Characteristics of the patients in the primary analysis
Sex (M:F)68:35
Median age65 (35-82)
Median size (long axis × short axis) (mm)18 (8-60) × 9 (4-42)
Final diagnosis (n)Pancreatic carcinoma67
Bile duct carcinoma21
Gallbladder carcinoma11
Ampullary carcinoma4
Table 2 Sensitivity, specificity, and accuracy with which CH-endoscopic ultrasonography, color Doppler endoscopic ultrasonography, and the standard endoscopic ultrasonography variables differentiate malignant from benign lymph nodes
Sensitivity (95%CI)Specificity (95%CI)Accuracy (95%CI)P value1
Short axis 13 mm or longer72% (34/47) (62-81)85% (74/87) (79-90)81% (108/134) (73-86)0.27
Long axis 20 mm or longer72% (34/47) (61-82)63% (55/87) (57-68)66% (89/134) (59-73)0.001
Round shape62% (29/47) (51-72)75% (65/87) (69-80)70% (94/134) (62-77)0.008
Sharp edge81% (38/47) (71-89)30% (26/87) (24-34)48% (64/134) (41-53)< 0.001
Hypoechogenicity66% (31/47) (55-76)61% (53/87) (55-66)63% (84/134) (55-70)< 0.001
CIV absent70% (33/47) (59-80)72% (63/87) (66-78)72% (96/134) (64-78)0.009
Heterogeneous (CH-EUS)83% (39/47) (77-89)91% (79/87) (86-94)88% (118/134) (82-93)
Table 3 Number of lymph nodes in the benign and malignant groups that exhibited heterogeneous and homogeneous enhancement on contrast-enhanced harmonic endoscopic ultrasonography
Number with each enhancement pattern
Final diagnosisHeterogeneousHomogeneousTotal
Malignancy39847
Benign87987
Total4787134
Table 4 Characteristics of the patients in the secondary analysis
Sex (M:F)32:19
Median age66 (37-79)
Median size (long axis × short axis) (mm)20 (8-60) × 10 (4-42)
Final diagnosis (n)Pancreatic carcinoma29
Bile duct carcinoma12
Gallbladder carcinoma7
Ampullary carcinoma3