Predicting liver metastasis of gastrointestinal tract cancer by diffusion-weighted imaging of apparent diffusion coefficient values

Table 1 Comparison of clinical data between the effective and ineffective groups

Groups	Average age (yr)	Maximum tumor diameter (cm)
		Before treatment	After 2 wk of treatment	After 12 wk of treatment
Effective group (n = 73)	57.7 ± 5.9	3.45 ± 0.81	3.29 ± 0.75	1.87 ± 0.38
Ineffective group (n = 83)	59.6 ± 6.2	3.62 ± 0.85	3.47 ± 0.88	3.45 ± 0.62
t value	1.953	1.274	1.365	18.874
P value	0.053	0.205	0.174	0

Table 2 Changes in apparent diffusion coefficient values before and after chemotherapy treatment between the effective and ineffective groups

Groups	Before treatment	After 2 wk of treatment	After 12 wk of treatment	After 2 wk of treatment		After 12 wk of treatment
				t value	P value	t value	P value
Effective group	1.01 ± 0.06	1.26 ± 0.11	1.34 ± 0.18	17.047	0.000	14.86	0.000
Ineffective group	1.24 ± 0.08	1.26 ± 0.05	1.22 ± 0.17	1.931	0.055	0.97	0.334
t value	2.747	1.491	1.783	/	/	/	/
P value	0.007	0.138	0.077	/	/	/	/

Table 3 Relationship between apparent diffusion coefficient values and tumor diameter changes

Correlation	r value	P value
Apparent diffusion coefficient (ADC) values before treatment vs mean maximum tumor diameter	0.124	0.108
ADC values 2 wk after treatment vs mean maximum tumor diameter after 2 wk of treatment	0.093	0.183
ADC values after 12 wk of treatment vs mean maximum tumor diameter after 12 wk of treatment	0.052	0.118
ADC values before treatment vs reduced percentage of the mean maximum tumor diameter after 12 wk of treatment	-0.718	0.001
Increased percentage of ADC values after 12 wk of treatment vs reduced percentage of maximum tumor diameter	0.742	0.002
Percent decrease in tumor size vs mean maximum diameter of metastatic tumors before treatment	-0.015	0.279