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©The Author(s) 2015.
World J Gastroenterol. Feb 28, 2015; 21(8): 2425-2432
Published online Feb 28, 2015. doi: 10.3748/wjg.v21.i8.2425
Published online Feb 28, 2015. doi: 10.3748/wjg.v21.i8.2425
Table 1 Clinical manifestations of small-volume chylous ascites following laparoscopic radical gastrectomy
Symptom | n (%) |
Abnormal blood leukocyte increase | 54 (94.7) |
Abdominal pain | 40 (70.1) |
Fever | 20 (35.1) |
Abdominal distension | 19 (33.3) |
Abdominal bleeding | 2 (3.51) |
Table 2 Comparison of the variables of patients with and without small-volume chylous ascites, according to a univariate analysis
Characteristic | SVCA (n = 57) | No SVCA (n = 1309) | P value |
Gender | 0.963 | ||
Male | 43 | 991 | |
Female | 14 | 318 | |
Age (yr) | 63.60 ± 9.344 | 61.18 ± 11.346 | 0.091 |
Preoperative anemia | 0.013 | ||
Present | 26 | 395 | |
Absent | 31 | 914 | |
Preoperative hypoproteinemia | 0.012 | ||
Present | 22 | 314 | |
Absent | 35 | 995 | |
Tumor size (cm) | 0.735 | ||
≥ 5 | 26 | 627 | |
< 5 | 31 | 682 | |
Tumor location | 0.179 | ||
Upper | 12 | 303 | |
Middle | 18 | 283 | |
Lower | 20 | 609 | |
Diffuse | 7 | 114 | |
Histology | 0.911 | ||
Differentiated | 24 | 599 | |
Undifferentiated | 33 | 710 | |
Tumor depth | 0.690 | ||
T1 | 15 | 319 | |
T2 | 6 | 147 | |
T3 | 13 | 388 | |
T4 | 23 | 455 | |
Surgical management | 0.481 | ||
Distal gastrectomy | 28 | 603 | |
Total gastrectomy | 29 | 706 | |
Lymph node status | 0.004 | ||
N0 | 12 | 480 | |
N1 | 9 | 195 | |
N2 | 16 | 201 | |
N3 | 20 | 433 | |
Resected LNs (n) | 35.12 ± 13.691 | 31.35 ± 11.494 | 0.045 |
Operative time (min) | 201.12 ± 66.076 | 192.24 ± 84.062 | 0.430 |
Table 3 Correlation between small-volume chylous ascites and perigastric lymph nodes metastasis (n)
LADG | P value | LATG | P value | |||
SVCA | No SVCA | SVCA | No SVCA | |||
No. 1 | 0.969 | 0.314 | ||||
+ | 1 | 31 | 5 | 138 | ||
- | 18 | 581 | 33 | 559 | ||
No. 2 | / | / | / | 0.896 | ||
+ | / | / | 8 | 153 | ||
- | 30 | 544 | ||||
No. 3 | 0.948 | 0.115 | ||||
+ | 7 | 221 | 18 | 420 | ||
- | 12 | 391 | 20 | 277 | ||
No. 4 | 0.692 | 0.161 | ||||
+ | 6 | 168 | 15 | 201 | ||
- | 13 | 444 | 23 | 496 | ||
No. 5 | 0.458 | 0.093 | ||||
+ | 4 | 91 | 1 | 79 | ||
- | 15 | 521 | 37 | 618 | ||
No. 6 | 0.353 | 0.837 | ||||
+ | 4 | 190 | 6 | 119 | ||
- | 15 | 422 | 32 | 578 | ||
No. 7 | 0.431 | 0.505 | ||||
+ | 1 | 67 | 9 | 200 | ||
- | 18 | 545 | 29 | 497 | ||
No. 8 | 0.014 | 0.035 | ||||
+ | 7 | 96 | 9 | 285 | ||
- | 12 | 516 | 29 | 412 | ||
No. 9 | 0.017 | 0.000 | ||||
+ | 6 | 78 | 32 | 240 | ||
- | 13 | 534 | 6 | 457 | ||
No. 10 | / | 0.126 | ||||
+ | / | / | 5 | 167 | ||
- | / | / | 33 | 530 | ||
No. 11 | 0.898 | 0.134 | ||||
+ | 2 | 59 | 5 | 165 | ||
- | 17 | 553 | 33 | 532 | ||
No. 12a | 0.579 | 0.182 | ||||
+ | 15 | 450 | 21 | 459 | ||
- | 4 | 162 | 17 | 238 |
Table 4 Multivariable analysis of the factors associated with the development of small-volume chylous ascites
Factor | P value | OR | 95%CI | |
Resected LNs (n) | 0.010 | 2.069 | 1.187 | 3.605 |
(≥ 32 vs < 32) | ||||
No. 8 metastasis | 0.039 | 2.102 | 1.037 | 4.261 |
(positive vs negative) | ||||
No. 9 metastasis | 0.000 | 4.019 | 2.011 | 8.030 |
(positive vs negative) | ||||
Preoperative anemia | 0.486 | 1.247 | 0.67 | 2.321 |
(present vs absent) | ||||
Preoperative hypoproteinemia | 0.076 | 0.566 | 0.302 | 1.062 |
(present vs absent) | ||||
N stage | 0.000 | |||
N1 vs N0 | 0.053 | 1.519 | 0.688 | 7.426 |
N2 vs N0 | 0.000 | 5.194 | 2.244 | 12.021 |
N3 vs N0 | 0.000 | 7.342 | 2.774 | 19.431 |
Table 5 Comparison of postoperative recovery between the small-volume chylous ascites and non-small-volume chylous ascites groups
Factor | SVCA (n = 57) | No SVCA (n = 1309) | P value |
Postoperative anal exhaust (d) | 3.54 ± 1.283 | 3.54 ± 1.343 | 0.963 |
Postoperative food intake (d) | 4.19 ± 2.326 | 4.62 ± 1.772 | 0.078 |
Postoperative hospital stay (d) | 25.14 ± 15.693 | 13.11 ± 5.894 | < 0.001 |
WBC count (POD1, × 109/L) | 12.5 ± 3.8 | 13.1 ± 4.8 | 0.376 |
WBC count (POD3, × 109/L) | 15.2 ± 2.4 | 12.2 ± 3.6 | 0.023 |
WBC count (POD5, × 109/L) | 17.6 ± 4.7 | 11.6 ± 2.2 | 0.018 |
WBC count (POD7, × 109/L) | 16.2 ± 5.8 | 10.9 ± 3.1 | 0.013 |
WBC count (discharge) | 8.1 ± 1.5 | 7.3 ± 2.2 | 0.541 |
- Citation: Lu J, Wei ZQ, Huang CM, Zheng CH, Li P, Xie JW, Wang JB, Lin JX, Chen QY, Cao LL, Lin M. Small-volume chylous ascites after laparoscopic radical gastrectomy for gastric cancer: Results from a large population-based sample. World J Gastroenterol 2015; 21(8): 2425-2432
- URL: https://www.wjgnet.com/1007-9327/full/v21/i8/2425.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i8.2425