Laparoscopic gastric bypass vs sleeve gastrectomy in obese Korean patients

Table 1 Preoperative demographics and clinical characteristics of the enrolled patients

	LSG (n = 104)	LRYGB (n = 236)	P value1
Age (yr)	31 (25-38)	38 (29-46)	< 0.001
Sex
Male	41 (39.4)	37 (15.7)	< 0.001
Female	63 (60.6)	199 (84.3)
Body weight (kg)	107.0 (95.0-130.8)	100.0 (87.0-116.8)	< 0.001
BMI (kg/m2)	38.6 (34.8-43.8)	37.2 (33.6-41.7)	0.024
Excess weight (kg)2	43.1 (33.5-62.6)	38.4 (28.1-52.6)	0.003
Comorbidities
Diabetes	19 (18.3)	84 (35.6)	0.001
Hypertension	28 (26.9)	88 (37.3)	0.082
Dyslipidemia	64 (67.4)	116 (68.2)	0.892
OSA
Confirmed	10 (10.5)	24 (14.1)	0.514
Suspicious	4 (4.2)	11 (6.5)
Arthropathy	12 (12.6)	31 (18.2)	0.298
GERD	14 (13.5)	19 (8.1)	0.163
PCOS3	12 (19.0)	30 (15.1)	0.554
No. of comorbidities	1.5 (1-2)	2 (1-3)	0.031

Data are presented as n (%) or median (interquartile range).

¹Mann-Whitney U test for continuous variables and Pearson’s χ² test or Fisher’s exact test for categorical variables were applied;

²The excess weight was calculated from the ideal weight using a BMI of 23 kg/m² as the upper limit of normal according to the World Health Organization recommended definition of obesity for Asians;

³The incidence among female patients. LSG: Laparoscopic sleeve gastrectomy; LRYGB: Laparoscopic Roux-en-Y gastric bypass; BMI: Body mass index; OSA: Obstructive sleep apnea; GERD: Gastro-esophageal reflux disease; PCOS: Polycystic ovarian syndrome.

Table 2 Surgical outcomes according to the surgical procedures

	LSG (n = 104)	LRYGB (n = 236)	P value1
Combined operation	5 (4.8)	19 (8.1)	0.282
Operating time (min)	100 (90-115)	130 (110-150)	< 0.001
Intraoperative blood loss	100 (50-150)	100 (50-200)	0.010
Length of hospital stay (d)	1 (1-2)	2 (1-2)	0.003
Intraoperative complication	1 (1.0)	4 (1.7)	> 0.999
Postoperative complication2
No	95 (91.3)	202 (85.6)	0.351
Yes
Mild	7 (6.7)	25 (10.6)
Moderate	0 (0)	5 (2.1)
Severe	2 (1.9)	4 (1.7)
Re-admission	3 (2.9)	8 (3.4)	> 0.999

Data are presented as n (%) or median (interquartile range).

¹Mann-Whitney U test for continuous variables, and Pearson’s χ² test or Fisher’s exact test for categorical variables were applied;

²The severity of postoperative complications were classified according to the Accordion Severity Grading System. LSG: Laparoscopic sleeve gastrectomy; LRYGB: Laparoscopic Roux-en-Y gastric bypass.

Table 3 Anthropometric outcomes at last follow-up

	LSG (n = 104)	LRYGB (n = 236)	P value1
Mean follow-up period (mo)	21.0 (14.5-28.0)	18.0 (12.0-24.0)	0.012
At last follow up
Body weight (kg)	81.5 (64.0-98.5)	72.0 (63.0-85.0)	< 0.001
BMI (kg/m2)	28.5 (24.5-34.2)	27.3 (24.1-30.2)	0.014
%EWL (%)2	63.5 (44.8-88.0)	71.2 (53.7-91.1)	0.073
%TWL (%)	25.0 (19.4-32.9)	26.7 (20.0-32.4)	0.394
EWL < 50% at 1 year	18 (21.2)	23 (13.6)	0.148
Revision	5 (4.8)	1 (0.4)	0.011

Data are presented as n (%) or median (interquartile range).

¹Mann-Whitney U test for continuous variables and Pearson’s χ² test or Fisher’s exact test for categorical variables were applied;

²A BMI of 23 kg/m² was adopted as the upper limit of normal to calculate %EWL according to the World Health Organization recommended definition of obesity for Asians. LSG: Laparoscopic sleeve gastrectomy; LRYGB: Laparoscopic Roux-en-Y gastric bypass; BMI: Body mass index; EWL: Excess weight loss; TWL: Total weight loss.

Table 4 Long-term complications (> 30 d) n (%)

LSG (n = 104)		LRYGB (n = 236)
GERD	28 (26.9)	Marginal ulcer	64 (27.1)
Anemia	4 (3.8)	Confirmed by endoscopy	15 (6.4)
		Clinically suspicious	49 (20.8)
		Anemia	53 (22.5)
		GERD	11 (4.7)
		Peterson hernia	3 (1.3)
		Ventral hernia	3 (1.3)

LSG: Laparoscopic sleeve gastrectomy; LRYGB: Laparoscopic Roux-en-Y gastric bypass; GERD: Gastro-esophageal reflux disease.