Fluid resuscitation in acute pancreatitis: Normal saline or lactated Ringer's solution?

Table 1 Demographic data of patients in the Ringer’s solution and normal saline groups n (%)

	1-RL group (n = 40)	2-NS group (n = 63)
Age (yr), mean ± SD	49.2 ± 18.0	52.5 ± 17.6
Male	30 (75)	38 (60.3)
Female	10 (25)	25 (39.7)
BMI (kg/m2), mean ± SD	27.6 ± 5.0	26.3 ± 5.4

The 1-Ringer’s solution (1-RL) group with standard fluid resuscitation with lactated Ringer’s 1000 mL solution; The 2-normal saline (2-NS) group with standard fluid resuscitation with 1000 mL normal saline. BMI: Body mass index.

Table 2 Prediction of severe acute pancreatitis in the Ringer’s solution and normal saline groups n (%)

	1-RL	2-NS	P value
BISAP ≥ 3	8 (20.0)	8 (12.7)	0.405
uNGAL ≥ 73 ng/mL	15 (37.5)	11 (17.5)	0.035

The 1-Ringer’s solution (1-RL) group with standard fluid resuscitation with lactated Ringer’s 1000 mL solution; The 2-normal saline (2-NS) group with standard fluid resuscitation with 1000 mL normal saline. BISAP: Bedside index of severity in acute pancreatitis; uNGAL: Urinary neutrophil gelatinase-associated lipocalin.

Table 3 The distribution of acute pancreatitis severity between the two groups n (%)

P = 0.187	Total(n = 103)	1-RL group(n = 40)	2-NS group(n = 63)
Mild AP	64 (62.1)	22 (55.5)	42 (66.7)
Moderate AP	26 (25.24)	10 (25.5)	16 (24.4)
Severe AP	13 (12.62)	8 (20.0)	5 (7.9)

The 1-Ringer’s solution (1-RL) group with standard fluid resuscitation with lactated Ringer’s 1000 mL solution; The 2-normal saline (2-NS) group with standard fluid resuscitation with 1000 mL normal saline. AP: Acute pancreatitis.

Table 4 Clinical data of patients in the Ringer’s solution and normal saline groups n (%)

	1-RL	2-NS	P value
Pancreatic necrosis	10 (25.0)	12 (19)	0.637
Enteral nutrition	23 (57.5)	17 (27)	0.534
Hospital stay	9 d	9 d	0.776
Fatal AP	5 (12.5)	3 (4.7)	0.256

The 1-Ringer’s solution (1-RL) group with standard fluid resuscitation with lactated Ringer’s 1000 mL solution; The 2-normal saline (2-NS) group with standard fluid resuscitation with 1000 mL normal saline. AP: Acute pancreatitis.