Kim A, Park WY, Shin N, Lee HJ, Kim YK, Lee SJ, Hwang CS, Park DY, Kim GH, Lee BE, Jo HJ. Cardiac mucosa at the gastroesophageal junction: An Eastern perspective. World J Gastroenterol 2015; 21(30): 9126-9133 [PMID: 26290639 DOI: 10.3748/wjg.v21.i30.9126]
Corresponding Author of This Article
Do Youn Park, MD, PhD, Department of Pathology, BioMedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, 1-10 Ami-Dong, Seo-Gu, Busan 602-739, South Korea. pdy220@pusan.ac.kr
Research Domain of This Article
Pathology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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World J Gastroenterol. Aug 14, 2015; 21(30): 9126-9133 Published online Aug 14, 2015. doi: 10.3748/wjg.v21.i30.9126
Table 1 Relationship between mucosal type and endoscopic findings n (%)
Assessment
Mucosa type
OM/OCM (n = 20)
CM (n = 41)
P value
Los Angeles classification
N
15 (75.0)
18 (43.9)
0.022
M, A, B, C, D
5 (25.0)
23 (56.1)
Hill grade
Normal (1, 2)
16 (80.0)
27 (65.9)
0.255
Reflux (3, 4)
4 (20.0)
14 (34.1)
Hiatal hernia
Absent
15 (75.0)
22 (53.7)
0.109
Present
5 (25.0)
19 (46.3)
Table 2 Relationship between mucosal type and severity of inflammation n (%)
Assessment
Mucosa type
OM/OCM (n = 20)
CM (n = 41)
P value
Mononuclear cell infiltration
Mild
11 (55.0)
6 (14.6)
0.001
Moderate, marked
9 (45.0)
35 (85.4)
Neutrophil infiltration
Absent
17 (85.0)
19 (46.3)
0.004
Mild, moderate, marked
3 (15.0)
22 (53.7)
Intestinal metaplasia
Absent
17 (85.0)
28 (68.3)
0.164
Present
3 (15.0)
13 (31.7)
Helicobacter pylori infection
Absent
16 (80.0)
33 (80.5)
0.964
Present
4 (20.0)
8 (19.5)
Table 3 Relationship between carditis and endoscopic findings n (%)
Assessment
Carditis
Absent (n = 24)
Present (n = 37)
P value
Los Angeles classification
N
18 (75.0)
15 (40.5)
0.008
M, A, B, C, D
6 (25.0)
22 (59.5)
Hill grade
Normal (1, 2)
20 (83.3)
23 (62.2)
0.077
Reflux (3, 4)
4 (16.7)
14 (37.8)
Hiatal hernia
Absent
17 (70.8)
20 (54.1)
0.190
Present
7 (29.2)
17 (45.9)
Helicobacter pylori infection
Absent
20 (83.3)
29 (78.4)
0.634
Present
4 (16.7)
8 (21.6)
Table 4 Logistic regression analysis between oxyntic mucosa/oxyntocardiac mucosa and cardiac mucosa
Assessment
Adjusted odds ratio
95%CI
P value
Mononuclear cell infiltration
4.230
1.003-17.833
0.049
Neutrophil infiltration
4.296
0.958-19.267
0.057
Los Angeles classification
2.969
0.771-11.430
0.114
Age
1.038
0.989-1.089
0.130
Citation: Kim A, Park WY, Shin N, Lee HJ, Kim YK, Lee SJ, Hwang CS, Park DY, Kim GH, Lee BE, Jo HJ. Cardiac mucosa at the gastroesophageal junction: An Eastern perspective. World J Gastroenterol 2015; 21(30): 9126-9133