Copyright
©The Author(s) 2015.
World J Gastroenterol. Jul 14, 2015; 21(26): 7944-7953
Published online Jul 14, 2015. doi: 10.3748/wjg.v21.i26.7944
Published online Jul 14, 2015. doi: 10.3748/wjg.v21.i26.7944
Table 1 Hereditary syndromes associated with high risk of colorectal cancer and principal involved genes
| Syndrome | Mendelian pattern | Gene |
| Lynch syndrome | Autosomal dominant | hMLH1 |
| Familial adenomatous | Autosomal dominant | APC |
| Attenuated FAP | Autosomal dominant | APC FAP |
| MUTYH-associated polyposis | Autosomal recessive | MUTYH |
| Peutz–Jeghers syndrome | Autosomal dominant | STK11 |
| Juvenile polyposis syndrome | Autosomal dominant | SMAD4 |
- Citation: Del Vecchio Blanco G, Paoluzi OA, Sileri P, Rossi P, Sica G, Pallone F. Familial colorectal cancer screening: When and what to do? World J Gastroenterol 2015; 21(26): 7944-7953
- URL: https://www.wjgnet.com/1007-9327/full/v21/i26/7944.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i26.7944