Management of duodenal stump fistula after gastrectomy for gastric cancer: Systematic review

Table 1 Review of the literature

Ref. (year)	Country	Period	Patients, n	Study	Healing time in days (mean)	Conservative treatment	Surgical treatment	Endoscopic treatment	Percutaneous transhepatic biliary diversion	Percutaneus treatment (drainage of abscesses or duodenostomy)	Results	Complications
Garden et al[15] 1988	United Kingdom	1979-1985	13	RS	17-71(35)	12	1	0	0	9	12 spontaneous closure 1 need surgical	nr
Bloch et al[19] 1989	France	1989	1	Case	5 wk	0	0	0	0	1	Solved	0
Kyzer et al[12]1997	Israel	1991-1994	2	RS	nr	1	1	0	0	0	The pt. Surgically treated dead for sepsis	1pt. dead
Wong et al[11] 2000	China	1993-1997	1	Case	2	1	0	1	0	0	Closure in 2 day	0
Oh et al[14] 2009	South Korea	1987-2004	5	RS	10-28(18)	0	5	0	0	0	Solved
Lee et al[20] 2009	South Korea	2009	1	Case	17	0	0	1	0	0	Solved
Cozzaglio et al[7] 2010	Italy	1991-2006	68	MT/RS	1-1035(median 19)	51	27	NR	4	17	Non surgical Solved in25 day (7-65); surgical 58d. (1-1035)	51 (75%), 11 (16.2%) pts. Dead
Cozzaglio et al[8] 2011	Italy	2005-2010	6	PR	20-604(median 43)	0	0	0	6	0	3 Solved	3pts. dead (50%)
Curcio et al[13] 2012	Italy	2012	1	Case	60	0	0	1	0	0	Closure in 2 months
Blouhos et al[22] 2013	Greece	2013	1	Case	45	0	1	0	0	0	Solved
Orsenigo et al[23] 2014	Italy	1987-2012	32	RS	31.2 ± 19.7 (mean conservative, PTBD and drainage), 45.2 ± 57.4 (mean surgical)	11	13	0	3	5	Conservative:11/11 solvedPTBD 3/3 solvedDrainage 5/5 solvedSurgical:10/13 solved3/13 death	1 pt. Bleeding2 pts. Septic shock
Kim et al[24] 2014	South Korea	2002-2012	13	RS	14-134 (57.3 surgical), 8-18 (11.7 mean conservative)	3	10	0	0	0	Conservative: 3/3 solvedSurgical 8/10 solved2/10 death	2 pts. dead
Vasiliadis et al[25] 2014	Greece	2014	1	case	17	0	1	0	0	0	1 surgical solved in 17 days
Tot. (1988-2014), n (%)		1979-2014	145		1-1035	79 (54.5)	59 (40.7)	3 (2.1)	13 (9.0)	32 (22.1)

RS: Retrospective study; PR: Prospective study; MT: Multicenter trial; PTBD: Percutaneous transhepatic biliary diversion.