Autologous mobilized peripheral blood CD34+ cell infusion in non-viral decompensated liver cirrhosis

Table 1 Baseline characteristics between control and study group (mean ± SD)

Parameter	Control group(n = 23)	Study group(n = 22)	P value
Age (yr)	47.35 ± 12.54	48.91 ± 9.25	0.64
Sex ratio (M:F)	20:3	16:6	0.072
Hemoglobin (g/dL)	9.29 ± 1.86	9.15 ± 1.60	0.79
Platelet count (Lakhs/mm3)	0.92 ± 0.27	1.1 ± 0.72	0.24
Total bilirubin (mg/dL)	4.78 ± 4.06	3.55 ± 2.12	0.21
AST (IU/mL)	101.61 ± 174.41	67.14 ± 55.99	0.30
ALT (IU/mL)	77.87 ± 125.54	32.45 ± 17.07	0.10
Albumin (mg/dL)	2.7 ± 0.35	2.55 ± 0.35	0.16
INR	1.72 ± 0.53	1.80 ± 0.52	0.62
Creatinine (mg/dL)	1.08 ± 0.38	1.02 ± 0.29	0.56
MELD score	18.73 ± 5.29	18.28 ± 3.50	0.74

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; IU: International unit; INR: International normalized ratio; MELD: Model for end-stage liver disease score.

Table 2 Comparison between control and study group at 1 mo (mean ± SD)

Parameter	Control group(n = 23)	Study group(n = 22)	P value
Platelet count (Lakhs/mm3)	0.87 ± 0.23	0.94 ± 0.41	0.48
Total bilirubin (mg/dL)	4.63 ± 3.16	3.37 ± 1.91	0.11
AST (IU/mL)	80.78 ± 74.98	68 ± 24.98	0.45
ALT (IU/mL)	55.13 ± 61.34	41.73 ± 20.56	0.34
Albumin (mg/dL)	2.43 ± 0.42	2.83 ± 0.36	0.001
INR	1.78 ± 0.65	1.67 ± 0.49	0.50
Creatinine (mg/dL)	1.24 ± 0.50	1.01 ± 0.32	0.06
MELD score	19.42 ± 6.52	15.73 ± 3.35	0.02

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; IU: International unit; INR: International normalized ratio; MELD: Model for end-stage liver disease score.

Table 3 Comparison between control and study group at 3 mo (mean ± SD)

Parameter	Control group (n = 17)	Study group(n = 18)	P value
Platelet count (Lakhs/mm3)	0.91 ± 0.36	1.16 ± 0.71	0.21
Total bilirubin (mg/dL)	5.89 ± 7.13	3.82 ± 3.30	0.27
AST (IU/mL)	70.29 ± 43.57	48.39 ± 15.79	0.05
ALT (IU/mL)	49.18 ± 66.59	39.44 ± 19.02	0.55
Albumin (mg/dL)	2.65 ± 0.53	2.83 ± 0.33	0.24
INR	1.88 ± 0.48	1.61 ± 0.30	0.05
Creatinine (mg/dL)	1.42 ± 0.70	0.96 ± 0.33	0.01
MELD score	19.94 ± 6.68	15.75 ± 5.13	0.04
Frequency of tap in last 3 mo	1.59 ± 1.06	1.28 ± 0.75	0.32

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; IU: International unit; INR: International normalized ratio; MELD: Model for end-stage liver disease score; tap: Therapeutic paracentesis.