Assessment of liver fibrosis by Fibroscan as compared to liver biopsy in biliary atresia

Table 1 Relevant information of different liver fibrosis stages

	F2 (n = 4)	F3 (n = 20)	F4 (n = 7)	P-value
LSM (kPa)	9.10 ± 3.30	11.02 ± 3.31	22.86 ± 12.43	0.001
AST (IU/L)	251.25 ± 173.05	286.59 ± 147.11	328.01 ± 192.54	0.732
ALT (IU/L)	152.50 ± 142.69	180.54 ± 109.90	181.19 ± 92.99	0.893
TBIL (μmol/L)	176.98 ± 43.13	184.81 ± 37.06	194.81 ± 59.87	0.791
DBIL (μmol/L)	89.93 ± 27.46	86.21 ± 13.51	91.64 ± 27.04	0.790
IBIL (μmol/L)	87.05 ± 16.61	98.60 ± 37.29	103.17 ± 38.92	0.773
ALP (U/L)	471.75 ± 92.69	611.37 ± 310.79	626.44 ± 245.08	0.636
GGT (U/L)	631.00 ± 522.17	736.62 ± 587.59	569.89 ± 272.86	0.756
TBA (μmol/L)	103.73 ± 34.29	107.07 ± 35.01	144.09 ± 53.60	0.105
APRI	1.76 ± 1.12	2.34 ± 1.93	2.72 ± 2.36	0.741
Age at operation (d)	73.00 ± 18.67	70.70 ± 20.25	91.00 ± 23.49	0.100

LSM: Liver stiffness measurement; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; TBA: Total bile acid; APRI: Aspartate aminotransferase to platelet ratio index.