Liver transplantation for a giant mesenchymal hamartoma of the liver in an adult: Case report and review of the literature

Table 1 Cases of adult mesenchymal hamartomas of the liver reported in the literature

No.	Ref.	Year	Sex	Age (yr)	Clinical manifestation	Size (cm)	Gross appearance(cystic or solid)	Liver lobe(s)affected	Surgical treatment
1	Yamamura et al[26]	1976	F	22	NA	NA	Cystic	Both	NA
2	Grases et al[27]	1979	F	19	Abdominal pain, jaundice, hepatomegaly	24 × 19 × 8	Cystic	Left	Left hepatic lobectomy
3	Li et al[28]	1983	F	21	Asymptomatic	17 × 10	Cystic	Right	Hemihepatectomy
4	Kawata et al[29]	1984	F	43	NA	22 × 15 × 10	Solid	Left	NA
5	Ishizuka et al[30]	1985	M	59	NA	30 × 28 × 12	Cystic	Right	NA
6	Kawakami et al[31]	1986	M	67	NA	NA	Cystic	Right	NA
7	Jennings et al[32]	1987	F	32	Asymptomatic	14 × 11	Cystic	Left	Left hepatic lobectomy
8	Kato et al[33]	1988	M	66	Asymptomatic	NA	Solid	Left	Left hepatic lobectomy
9	Gutierrez et al[34]	1988	F	30	NA	18	Both	Both	Non-resectable
10	Gramlich et al[35]	1988	F	28	Abdominal distention, hepatomegaly	30 × 20 × 14	Solid	Right	Right hepatic trisegmentectomy
11	Alanen et al[36]	1989	F	20	Asymptomatic	6 × 8	Cystic	Left	Left hepatic lobectomy
12	Ito et al[37]	1989	F	43	NA	16 × 16 × 7.7	Cystic	Both	NA
13	Urabe et al[38]	1990	F	39	Asymptomatic	1.2	Solid	Left	Left hepatic lobectomy
14	Drachenb et al[39]	1991	F	69	Asymptomatic	26 × 20 × 11.5	Cystic	Left	NA
15	Wada et al[40]	1992	M	62	Asymptomatic	6 × 6 × 4.5	Solid	Left	Hepatectomy
16	Chau et al[41]	1994	M	53	Abdominal pain	20 × 14 × 10	Cystic	Right	NA
17	Megremis et al[42]	1994	F	56	Abdominal pain	7.5	Cystic	Both	NA
18	Yamamoto et al[43]	1994	M	52	Abdominal discomfort, weight loss	6 × 4 × 3.5	Cystic	Left	Lateral segmentectomy
19	Chung et al[44]	1999	F	57	Abdominal discomfort, weight loss	6 × 4 × 3.5	Solid	Right	Right hepatectomy
20	Papastratis et al[45]	2000	F	21	Abdominal pain, abdominal mass	17 × 10	Cystic	Right	Right hepatectomy
21	Cook et al[13]	2002	F	46	Abdominal pain	6 × 4 × 5	Cystic	Right	Right hepatectomy
22	Cook et al[13]	2002	F	66	Cough and shortness of breath	5 × 4 × 2	Cystic	Right	Right hepatectomy
23	Cook et al[13]	2002	F	63	Abdominal pain	11 × 16 × 24	Solid	Left	Left hepatic lobectomy
24	Mao et al[46]	2002	M	44	Abdominal discomfort	2 × 2	Solid	Left	Hepatectomy
25	Mao et al[46]	2002	F	43	Asymptomatic	3 × 4 × 4	Cystic	Right	Right hepatectomy
26	Mao et al[46]	2002	M	76	Abdominal pain	4 × 5 × 4	Cystic	Right	Right hepatectomy
27	Brkic et al[47]	2003	M	38	Abdominal pain	8 × 5	Solid	Right	Right hepatectomy
28	Kim et al[48]	2003	M	NA	Asymptomatic	5	Both	Right	NA
29	Yesim et al[12]	2005	F	54	NA	2.5 × 2.5 × 1.5	Cystic	Left	Total cystectomy
30	Yesim et al[12]	2005	F	51	NA	6 × 7 × 8	Cystic	Right	Unroofing procedure
31	Kim et al[49]	2006	F	40	Asymptomatic	5 × 5	Cystic	Right	Right hepatectomy
32	Ayadi-Kaddour et al[50]	2006	F	21	NA	11 × 5	Cystic	Left	NA
33	Hernández et al[25]	2006	M	51	NA	19 × 13	Solid	Right	Liver transplantation (4th reported1)
34	Chang et al[51]	2006	M	79	Asymptomatic	2 × 2	NA	Right	NA
35	Chang et al[51]	2006	F	39	Asymptomatic	5 × 5	Cystic	NA	NA
36	Li et al[17]	2007	F	33	Abdominal distention	16	Both	Both	NA
37	Mori et al[52]	2008	F	36	Abdominal distention	20 × 15 × 10	Cystic	Right	Right hemihepatectomy
38	Giunippero et al[53]	2009	M	87	Abdominal distention	20 × 20	Cystic	Right	Hemihepatectomy
39	Nakajo et al[54]	2009	M	38	Asymptomatic	5 × 5	Solid	Right	Right hepatectomy
40	Klaassen et al[5]	2010	F	53	NA	9 × 9 × 7.5	Cystic	Right	Hepatectomy
41	Kulkarni et al[55]	2010	F	20	Abdominal mass, abdominal pain	14 × 11	cystic	Right	Mass resection
42	Tucker et al[56]	2012	W	74	Abdominal distention, abdominal pain	18 × 15 × 13	cystic	Left	Left hepatectomy
43	Liu et al[57]	2013	M	42	Asymptomatic	1.5 × 1.0 × 1.0	solid	Left	Hepatectomy
44	Lakić et al[58]	2014	M	44	Asymptomatic	2.9 × 3.1 × 3.5	NA	Left	Hepatectomy
45	Sharma et al[59]	2014	M	81	Abdominal distention	21.8 × 12.3 × 18.6	cystic	Left	Hepatectomy
46	Current case	2014	F	34	abdominal discomfort, dyspnea	41 × 32 × 31	cystic	Both	Liver transplantation (5th reported1)

¹The first three cases of liver transplantation for mesenchymal hamartomas of the liver were reported in pediatric patients. NA: Not available.