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©The Author(s) 2015.
World J Gastroenterol. Apr 14, 2015; 21(14): 4284-4292
Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4284
Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4284
Table 1 Baseline characteristics of subjects in the different groups n (%)
Non-HBV infected (n = 105) | HBsAg(-)/HBcAb(+) (n = 32) | HBsAg(+) (n = 25) | P value | |
Gender | 0.582 | |||
Male | 69 (65.71) | 22 (68.75) | 14 (56) | |
Female | 36 (34.29) | 10 (31.25) | 11 (44) | |
Age (yr) | 31.35 ± 11.88 | 32 ± 10.31 | 32.48 ± 9.66 | 0.887 |
Type of disease1 | 0.576 | |||
Acute myeloid leukemia | 44 (41.90) | 18 (56.25) | 15 (60) | |
Acute lymphoblastic leukemia | 30 (28.57) | 6 (18.75) | 6 (24) | |
Aplastic anemia | 16 (15.24) | 4 (12.50) | 1 (4) | |
Others | 15 (14.29) | 4 (12.50) | 3 (12) | |
Methods of transplantation | 0.548 | |||
Sibling | 80 (76.19) | 21(65.63) | 20 (80) | |
Unrelated | 21 (20.00) | 9 (28.13) | 3 (12) | |
Haploidy | 4 (3.81) | 2 (6.25) | 2 (8) |
Table 2 Complications of subjects in the different groups n (%)
Non-HBV infected (n = 105) | HBsAg(-)/HBcAb(+) (n = 32) | HBsAg(+) (n = 25) | P value | |
GVHD | ||||
Acute | 39 (37.14) | 15 (46.88) | 10 (40) | 0.614 |
Chronic | 41(39.05) | 13 (40.63) | 10 (40) | 0.986 |
Involvement1 | 0.366 | |||
Extensive | 29 (70.73) | 10 (76.92) | 5 (50) | |
Limited | 12 (29.27) | 3 (23.08) | 5 (50) | |
Grade1 | 0.089 | |||
I | 2 (5.13) | 3 (20) | 2 (20) | |
II | 19 (48.72) | 2 (13.33) | 2 (20) | |
III | 16 (41.03) | 7 (46.67) | 4 (40) | |
IV | 2 (5.13) | 3 (20) | 2 (20) | |
Drug-induced liver injury | 27 (25.71) | 6 (18.75) | 7 (28) | 0.717 |
Organ injury | 34 (82.93) | 11 (68.75) | 9 (90) | 0.372 |
Death | 39 (37.14) | 13 (40.63) | 13 (52) | 0.401 |
Time of granular cells engraftment (d), median (range) | 12 (7-35) | 12 (9-20) | 10 (8-19) | 0.091 |
Time of megakaryocytic cells engraftment (d), median (range) | 15 (9-50) | 15 (9-49) | 15 (9-48) | 0.880 |
- Citation: Liao YP, Jiang JL, Zou WY, Xu DR, Li J. Prophylactic antiviral therapy in allogeneic hematopoietic stem cell transplantation in hepatitis B virus patients. World J Gastroenterol 2015; 21(14): 4284-4292
- URL: https://www.wjgnet.com/1007-9327/full/v21/i14/4284.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i14.4284