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©The Author(s) 2015.
World J Gastroenterol. Apr 14, 2015; 21(14): 4255-4260
Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4255
Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4255
Table 1 Clinicopathologic factors and prognosis
Clinicopathologic factors | No. of patients | Survival (%) | P valuea | |
3-yr | 5-yr | |||
Total cases | 78 | 47.26 | 23.99 | |
Age (yr) | 0.388 | |||
≤ 60 | 46 | 57.14 | 28.57 | |
> 60 | 32 | 45.22 | 26.65 | |
Sex | 0.748 | |||
Male | 51 | 46.92 | 21.90 | |
Female | 27 | 48.48 | 36.36 | |
Duration of surgery (min) | 0.763 | |||
≤ 300 | 41 | 46.27 | 27.76 | |
> 300 | 37 | 47.98 | 18.66 | |
Intraoperative blood loss (mL) | 0.337 | |||
≤ 500 | 47 | 57.14 | 28.57 | |
> 500 | 31 | 46.34 | 26.42 | |
Differentiation degree | < 0.01 | |||
Highly | 24 | 61.32 | 33.45 | |
Moderately | 44 | 50.00 | 28.04 | |
Poorly | 10 | 23.08 | 15.38 | |
Perineural invasion | 0.435 | |||
Yes | 57 | 38.72 | 14.75 | |
No | 21 | 68.38 | 48.84 | |
Tumor embolism | 0.183 | |||
Yes | 3 | 33.33 | 33.33 | |
No | 75 | 47.94 | 25.68 | |
T stage | 0.369 | |||
T1 | 2 | 100 | 50 | |
T2 | 7 | 53.07 | 33.77 | |
T3 | 24 | 46.05 | 21.98 | |
T4 | 45 | 37.40 | 18.70 | |
Total number of lymph node dissected | 0.179 | |||
≤ 15 | 30 | 45.92 | 26.53 | |
> 15 | 48 | 39.39 | 26.26 | |
Lymph node metastasis | 0.010 | |||
Yes | 55 | 37.74 | 17.56 | |
No | 23 | 70.13 | 28.59 | |
MLNR | 0.002 | |||
0 | 23 | 70.13 | 28.59 | |
0-0.2 | 12 | 54.01 | 21.60 | |
0.2-0.5 | 18 | 48.34 | 18.84 | |
> 0.5 | 25 | 33.67 | 10.03 | |
TNM stage | 0.044 | |||
I | 2 | 54.83 | 27.95 | |
II | 26 | 41.67 | 21.03 | |
III | 50 | 35.06 | 17.53 | |
Cutting edge | 0.043 | |||
Negative | 75 | 54.36 | 25.02 | |
Positive | 3 | 33.33 | 10.00 | |
Postoperative chemotherapy | 0.055 | |||
Yes | 64 | 54.55 | 22.02 | |
No | 14 | 46.80 | 22.40 |
Table 2 Multivariate analysis for predictive factors of extrahepatic cholangiocarcinoma patient survival
Factors | β | SD | χ2 | P value | HR | 95%CI |
MLNR | 0.75 | 0.19 | 15.01 | < 0.01 | 2.13 | 1.45–3.11 |
TNM stage | 0.67 | 0.26 | 6.55 | 0.011 | 1.97 | 1.17–3.31 |
- Citation: Zhang JW, Chu YM, Lan ZM, Tang XL, Chen YT, Wang CF, Che X. Correlation between metastatic lymph node ratio and prognosis in patients with extrahepatic cholangiocarcinoma. World J Gastroenterol 2015; 21(14): 4255-4260
- URL: https://www.wjgnet.com/1007-9327/full/v21/i14/4255.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i14.4255