Helicobacter pylori infection in patients with selective immunoglobulin E deficiency

Table 1 Clinical and laboratory characteristics of the subjects n (%)

Characteristic	Cases(n = 158)	Controls(n = 3160)	P value
Female	113 (71.5)	2147 (67.9)	0.38
Age, yr	44.3 ± 20.4	43.1 ± 22.5	0.51
Body mass index, kg/m2	26.2 ± 3.5	26.5 ± 3.4	0.29
Total IgE, kIU/L	0.3 ± 0.2	109.1 ± 77.6	< 0.01
WBC, n/mm3	7.1 ± 3.4	6.8 ± 3.1	0.23
Lymphocytes, n/mm3	2.4 ± 1.3	2.3 ± 1.1	0.26
Eosinophils, n/mm3	0.31 ± 0.14	0.32 ± 0.11	0.27
Basophils, n/mm3	0.15 ± 0.11	0.16 ± 0.09	0.18
Platelets, n× 108/mm3	259 ± 124	267 ± 129	0.44
Dyspepsia	43 (27.2)	718 (22.7)	0.47
H. pylori-positive dyspepsia1	32 (74.4)	223 (31.1)	< 0.01

¹Percentage reflects the proportion of dyspeptic subjects. WBC: White blood cell; IgE: Immunoglobulin E; H. pylori: Helicobacter pylori.

Table 2 Esophagogastroduodenoscopy findings in Helicobacter pylori-positive dyspeptic subjects n (%)

Characteristic	Cases(n = 19)	Controls(n = 94)	P value
Female	11 (57.9)	49 (52.1)	0.81
Age, yr	43.9 ± 10.2	42.5 ± 9.7	0.49
Gastritis	11 (57.9)	28 (29.8)	0.03
Antral predominant gastritis	7 (36.8)	21 (22.3)	0.24
Body predominant gastritis	1 (5.3)	5 (5.3)	1.00
Multifocal atrophic gastritis	3 (15.8)	2 (2.1)	0.03
Duodenal ulcer	12 (63.2)	15 (15.9)	< 0.01
Gastric ulcer	1 (5.3)	1 (1.1)	0.31
Treatment-refractory H. pylori infection	9 (47.4)	11 (11.7)	< 0.01

H. pylori: Helicobacter pylori.