Biodegradable stents in gastrointestinal endoscopy

Table 1 Cases series evaluating the outcomes of biodegradable stents with polydioxanone for refractory benign esophageal strictures

Ref.	Year	Type of study	n	Follow-up(mo)	Technical success	Complications	Clinical success
Dhar et al[23]	2009	CS	4	4	100%	Chest pain, 25%	50%
Vandenplas et al[15]	2009	CR	1	4	100%	0%	100%
Orive-Calzada et al[16]	2009	CR	1	3	100%	T. hyperplasia, 100%	0%
Stivaros et al[27]	2010	CS	2	7	100%	Chest pain, 50%	50%
						Stent migration, 50%
Bychkova et al[24]	2009	CR	1	4	100%	0%	100%
Hair et al[30]	2010	CR	1	8	100%	T. hyperplasia, 100%	0%
van Hooft et al[17]	2011	CS	10	6	100%	Chest pain, 20%	60%
Repici et al[29]	2010	CS	21	13.2	100%	Chest pain, 14%	45%
						Hemorrhage, 5%
						Stent migration, 9%
Nogales Rincon et al[21]	2011	CR	1	2	100%	Stent collapse, 100%	0%
Martín Cano et al[25]	2012	CS	3	4	100%	0%	100%
Griffiths et al[28]	2012	CS	7	4	96%	0%	76%
Canena et al[9]	2012	RCT	10	12	100%	Chest pain, 10%	30%
						Hemorrhage, 10%
						Stent migration, 20
						T. hyperplasia, 30%
Fischer et al[19]	2012	CS	2	12	100%	T. hyperplasia, 50%	50%
Dumoulin et al[20]	2012	CR	1	18	100%	T. hyperplasia, 100%	0%
Hirdes et al[22]	2012	CS	28	10	100%	Chest pain, 22%	25%
						Hemorrhage, 8%
Basha et al[18]	2013	CR	1	4	100%	0%	0%
Karakan et al[26]	2013	CS	7	15	100%	T. hyperplasia, 57%	43%

CR: Case report; CS: Case series; RCT: Randomized clinical trial; T. hyperplasia: Tissue hyperplasia.

Table 2 Cases series evaluating the outcomes of biodegradable stents with polydioxanone for benign intestinal and colonic strictures

Ref.	Year	Type of study	Indication	n	Follow-up(mo)	Technical success	Complications	Clinical success
Janík et al[37]	2011	CS	PS	3	5	100%	0%	66%
Rejchrt et al[8]	2009	CS	Stricturing CD	11	14	91%	Stent migration, 27%	64%
Toth et al[36]	2011	CR	PS	1	5	100%	0%	100%
Pérez Roldán et al[35]	2012	CS	PS and fistula	10	13	90%	Stent migration, 10%	50%
Repici et al[34]	2013	CS	PS	11	3	100%	Stent migration, 36%	45%
Rodrigues et al[39]	2013	CR	Stricturing CD	1	16	100%	0%	100%

CR: Case report; CS: Case series; RCT: Randomized clinical trial; CD: Crohn’s disease; PS: Postsurgical strictures.