Current issues in locally advanced colorectal cancer treated by preoperative chemoradiotherapy

Table 1 Local excision after preoperative chemoradiotherapy for rectal cancer n (%)

Ref	Year	n	inclusion	Complete remission	Local recurrence	Follow-up duration, mo	Overall survival
Kim et al[10]	2001	26	cT2-3	17 (65.4)	1 (3.8)	19	100%
			CR after PCRT
Bonnen et al[11]	2004	26	cT3N0 or N1	14 (53.8)	2 (7.7)	46	5 yr OS; 85%
			CR after PCRT
Huh et al[58]	2008	9	cT2-3N0 or N1	4 (44.4)	1 (11.1)	91	10 yr OS; 88.9%
Nair et al[59]	2008	44	cT2-3N0 or N1	19 (43.2)	4 (9.1)	64	5 yr OS; 84
			CR after PCRT
Guerrieri et al[9]	2008	145	cT2-3N0	17	8 (4)	81	100% (pT0-1)
							90% (pT2)
							77% (pT3)
Kundel et al[60]	2010	14	CR after PCRT	All	0	47	100%
Yu et al[17]	2013	40	cT2-3N0	19 (47.5)	4 (7.5)	38	3 yr DFS: 85.9%
Perez et al[61]	2013	27	cT2-3N0-2	3 (11.1)	4 (14.8)	15	1 yr DFS: 68%

CR: Complete remission; PCRT: Preoperative chemoradiotherapy (CRT); OS: Overall survival; DFS: Disese-free survival.