Three-Tesla magnetic resonance elastography for hepatic fibrosis: Comparison with diffusion-weighted imaging and gadoxetic acid-enhanced magnetic resonance imaging

Table 1 Comparison of three magnetic resonance parameters and aspartate aminotransferase to the platelet ratio index score between hepatic fibrosis group and non-hepatic fibrosis group

	Liver stiffness (kPa)		ADC (× 10-3 mm2/s)		CEI		APRI
	HF	nHF	HF	nHF	HF	nHF	HF	nHF
Sample size	23	19	23	19	23	19	23	19
Value range	1.44-10.46	1.46-3.28	0.80-1.32	0.96-1.46	0.44-2.04	1.33-2.02	0.18-3.00	0.12-1.52
Median	3.79	2.04	1.04	1.20	1.63	1.71	0.77	0.33
Mean ± SD	4.05 ± 2.06	2.1 ± 0.44	1.04 ± 0.11	1.21 ± 0.12	1.57 ± 0.38	1.7 ± 0.22	0.99 ± 0.67	0.42 ± 0.36
P value1	< 0.0001		0.0001		0.3002		0.0002

¹Mann-Whitney U test. ADC: Apparent diffusion coefficient; CEI: Contrast enhancement ratio; APRI: Aspartate aminotransferase to the platelet ratio index; HF: Hepatic fibrosis group; nHF: Non-hepatic fibrosis group; SD: Standard deviation.

Table 2 Correlation between three magnetic resonance parameters and aspartate aminotransferase to the platelet ratio index score in all patients

Variable Y	Liver stiffness	ADC	CEI
Variable X	APRI	APRI	APRI
Sample size	42	42	42
Spearman's coefficient of rank correlation (r)	0.773	-0.28	-0.321
95%CI for r	0.613-0.872	-0.538-0.026	-0.570-(-0.019)
P value1	< 0.0001	0.0723	0.038

¹Spearman’s correlation test. ADC: Apparent diffusion coefficient; CEI: Contrast enhancement ratio; APRI: Aspartate aminotransferase to the platelet ratio index.

Table 3 Correlation between three magnetic resonance parameters and aspartate aminotransferase to the platelet ratio index score in hepatic fibrosis group and non-hepatic fibrosis group

Variable Y	Liver stiffness		ADC		CEI
Variable X	APRI		APRI		APRI
Group	HF	nHF	HF	nHF	HF	nHF
Sample size	23	19	23	19	23	19
Spearman's coefficient of rank correlation (r)	0.731	0.411	-0.128	-0.0404	-0.217	-0.132
95%CI	0.457-0.879	-0.054-0.729	-0.3-0.513	-0.422-0.486	-0.578-0.214	-0.553-0.343
for r
P value1	0.0001	0.081	0.561	0.870	0.319	0.591

¹Spearman’s correlation test. ADC: Apparent diffusion coefficient; CEI: Contrast enhancement ratio; APRI: Aspartate aminotransferase to the platelet ratio index; HF: Hepatic fibrosis group; nHF: Non-hepatic fibrosis group.