Extraintestinal manifestations in a large series of Italian inflammatory bowel disease patients

Table 1 Clinical and demographic characteristics of inflammatory bowel disease patients

	Crohn’s disease	Ulcerative colitis
	n = 216	n = 595
Males/Females	131/85	306/289
Mean ± SD (age years at diagnosis)	31.9 ± 13.1	33.1 ± 13.7
Location/extension, n
Ileum	103	-
Ileum + colon	64	-
Colon	39	-
Upper gastrointestinal	10	-
Diffuse colitis	-	144
Left-sided colitis	-	353
Procto-sigmoiditis	-	98
Behaviour, n
Inflammatory	98	-
Fistulizing	37	-
Stricturing	79	-
Perianal Involvement	3
Smoke at diagnosis	98	140
Ex-smoke at diagnosis	17	131
No smoke at diagnosis	101	324

Table 2 Percentage of type of extraintestinal manifestations calculated in the inflammatory bowel disease population (811 pts) and in inflammatory bowel disease patients with extraintestinal manifestations (329 pts)

Type of EIMS	Percent in IBD pts (40.6%)	Percent in EiMS pts (100%)
Muscoloskeletal	29.6	72.9
Mucocutaneous	5.8	14.3
Ocular	3.2	7.9
Hepatobiliary	0.8	1.8
Endocrinological	1.2	3.1

EIMs: Extraintestinal manifestations; IBD: Inflammatory bowel disease.

Table 3 Total extraintestinal manifestations in ulcerative colitis (210) and Crohn’s disease (119) patients

Type of EIMs	CD (119 pts)	UC (210 pts)	P value
Muscoloskeletal	71	169	< 0.0001
Mucocutaneous	26	21	0.0049
Ocular	16	10	0.0093
Hepatobiliary	2	4	1.0000
Endocrinological	3	7	1.0000

CD: Crohn’s disease; UC: Ulcerative colitis; EIMs: Extraintestinal manifestations.