Correlation between hepatic blood flow and liver function in alcoholic liver cirrhosis

Table 1 Characteristics of patients with alcoholic liver cirrhosis

Characteristics
Patients (n)
Gender
Male	34
Female	1
Age (yr)
Average	58.9 ± 10.7
Range	37-76
Median	61

Data represent raw number of patients or mean ± SD.

Table 2 Hepatic tissue blood flow, retention rate of indocyanine green 15 min after administration, and liver function

PVTBF	(mL/100 mL/min)	30.2 ± 10.4
HATBF	(mL/100 mL/min)	20.0 ± 10.7
THTBF	(mL/100 mL/min)	50.3 ± 14.9
Alb	(g/dL)	3.50 ± 0.50
PT		72.0% ± 11.5%
ChE	(IU/L)	161 ± 70.8
BNP	(pg/mL)	63.2 ± 56.7
TBA	(μmol/L)	68.0 ± 51.8
NH3	(μg/dL)	59.4 ± 22.7
ICG R15		28.6% ± 13.5%
BTR		4.06 ± 1.24
BCAA	(μmol/L)	437.5 ± 89.4
Tyrosine	(μmol/L)	117.7 ± 32.8
IRI	(μg/dL)	12.8 ± 5.0

Data represent mean ± SD. PVTBF: Portal venous tissue blood flow; HATBF: Hepatic arterial tissue blood flow; THTBF: Total hepatic tissue blood flow; ICG R15: Retention rate of indocyanine green 15 min after administration; Alb: Albumin; PT: Prothrombin time; BNP: Brain natriuretic peptide; BTR: Branched amino acid and tyrosine ratio; NH₃: Ammonia; ChE: Cholinesterase; IRI: Immunoreactive insulin; TBA: Total bile acid.

Table 3 Correlation between hepatic tissue blood flow, retention rate of indocyanine green 15 min after administration, and liver function

	PVBTF		HATBF		THTBA		ICG R15
	r	P value	r	P value	r	P value	r	P value
Alb (g/dL)	0.2499	< 0.05	-0.0251	NS	0.0452	NS	-0.2156	< 0.05
NH3 (μg/dL)	-0.2428	0.0894	-0.1479	NS	-0.1307	NS	0.4318	< 0.01
PT	0.1475	NS	0.1947	NS	0.0690	NS	-0.4140	< 0.01
BNP (pg/mL)	-0.0231	NS	-0.0231	NS	0.0330	NS	0.3610	< 0.05
TBA (μmol/L)	-0.1810	NS	-0.0160	NS	0.0483	NS	0.5085	< 0.01
T Chol (mg/dL)	-0.0618	NS	0.2007	NS	0.0483	NS	0.4195	< 0.05
ChE (IU/L)	-0.0613	NS	0.0704	NS	0.0197	NS	-0.0952	NS
BTR	-0.1329	NS	0.2103	NS	0.0801	NS	-0.2378	NS
BCAA (μmol/L)	-0.3123	NS	0.2031	NS	-0.0220	NS	-0.3123	< 0.05
Tyrosine (μmol/L)	0.0644	NS	-0.0317	NS	-0.0078	NS	0.4740	< 0.01
IRI (μg/dL)	-0.0377	NS	0.0509	NS	-0.0509	NS	0.1251	NS

PVTBF: Portal venous tissue blood flow; HATBF: Hepatic arterial tissue blood flow; THTBF: Total hepatic tissue blood flow; Alb: Albumin; PT: Prothrombin time; BNP: Brain natriuretic peptide; BTR: Branched amino acid and tyrosine ratio; NH₃: Ammonia; ChE: Cholinesterase; IRI: Immunoreactive insulin; TBA: Total bile acid; BCAA: BCAA: Branched-chain amino acids; NS: Not significant.