Prospective Study
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 21, 2014; 20(43): 16306-16310
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16306
Table 1 Diagnostic characteristics of magnifying endoscopy with narrow-band imaging, magnifying endoscopy with acetic acid spray and narrow-band imaging, and magnifying endoscopy with crystal violet dye
M-NBIMA-NBIM-CV
Accuracy (95%CI)73% (63%-81%)73% (63%-81%)73% (63%-81%)
Sensitivity (95%CI)85% (71%-93%)80% (67%-90%)83% (69%-91%)
Specificity (95%CI)60% (45%-73%)64% (50%-77%)62% (48%-75%)
PPV (95%CI)68% (55%-79%)70% (56%-81%)69% (56%-80%)
NPV (95%CI)79% (36%-90%)76% (61%-87%)78% (62%-89%)
M-NBI: Magnifying endoscopy with narrow-band imaging; MA-NBI; Magnifying endoscopy with acetic acid spray and narrow-band imaging; M-CV: Magnifying endoscopy with crystal violet dye; PPV: Positive predictive value; NPV: Negative predictive value.
Table 2 Diagnostic characteristics of magnifying endoscopy with narrow-band imaging
High-confidence predictions(n = 52)Low-confidence predictions(n = 39)P value for high-confidence vs low-confidence predictions
Accuracy (95%CI)79% (66%-88%)64% (48%-77%)0.16
Sensitivity (95%CI)87% (70%-95%)81% (56%-94%)0.68
Specificity (95%CI)68% (47%-84%)52% (33%-71%)0.37
PPV (95%CI)79% (62%-90%)54% (35%-72%)0.08
NPV (95%CI)79% (56%-92%)80% (54%-94%)1.00
CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value.
Table 3 Diagnostic characteristics of magnifying endoscopy with acetic acid spray and narrow-band imaging
High-confidence predictions(n = 68)Low-confidence predictions(n = 23)P value for high-confidence vs low-confidence predictions
Accuracy (95%CI)79% (68%-87%)52% (36%-71%)0.02
Sensitivity (95%CI)83% (67%-92%)70% (39%-90%)0.69
Specificity (95%CI)76% (59%-87%)39% (18%-65%)0.04
PPV (95%CI)78% (63%-89%)47% (25%-70%)0.04
NPV (95%CI)81% (63%-91%)63% (30%-90%)0.35
CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value.
Table 4 Diagnostic characteristics of magnifying endoscopy with crystal violet dye
High-confidence predictions(n = 69)Low-confidence predictions(n = 22)P value for high-confidence vs low-confidence predictions
Accuracy (95%CI)81% (70%-88%)46% (27%-65%)0.002
Sensitivity (95%CI)92% (78%-98%)38% (13%-70%)0.002
Specificity (95%CI)68% (50%-82%)50% (27%-73%)0.330
PPV (95%CI)78% (64%-88%)30% (10%-61%)0.006
NPV (95%CI)88% (68%-96%)58% (32%-81%)0.090
CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value.