Effect of somatostatin in advanced gastric cancer after D2 radical gastrectomy

Table 1 Clinical pathological indicator of patients in the trial group and the control group

	Trial group	Control group	Statistic value	P value
Age	56.3 ± 15.0	55.7 ± 14.7	0.209	0.835
Sex (male/female)	31:30	34:25	0.560	0.454
BMI	22.3 ± 5.0	23.0±4.7	0.861	0.391
Tumor size	4.7 ± 2.9	4.6 ± 3.1	0.325	0.746
T stage (T1/T2/T3/T4a)	0/15/28/18	0/13/29/19	0.187	0.911
Borrmann type (I/II/III/IV)	6/15/31/9	7/16/29/7	1.761	0.623
Histological type (differentiated/undifferentiated)	31/30	32/29	0.033	0.856
Operation time	207.7 ± 39.8	218.0 ± 56.5	1.152	0.252
Blood loss	211.3 ± 77.6	203.7 ± 54.6	0.617	0.538
Number of lymph nodes	29.3 ± 10.5	28.5 ± 8.6	0.479	0.633
Anastomotic method (billroth I/II Roux-en-Y)	0/35/26	0/34/25	0.146	0.702
Gastrectomy method (proximal/distal/total)	0/35/26	0/34/25	0.146	0.702
Lymph node dissection method (D2/D2PRO)	31/20	28/21	0.082	0.775
With organ resection (yes/no)	11/50	12/47	0.103	0.748
TNM stage (1/2/3/4)	0/18/33/10	0/16/32/9	0.050	0.975

Table 2 Post-operative complications in the trial group and the control group

Complication	Trial group	Control group	P-value
Pancreatic fistula	2	3	0.484
Stoma fistula	1	0	0.508
Peritoneal effusion or abscess	1	6	0.046
Bowel obstruction	0	1	0.492
Pneumonia	2	0	0.256
Chylous fistula	3	3	0.644
Incision infection or dehiscence	2	1	0.513
Post-operative pancreatitis	1	2	0.487
Total	14	17	0.463

Table 3 Gastric and peritoneal drainage volumes and duration in the study group and the control group

	Study group	Control group	Statistic value	P-value
Mean daily drainage volume of gastric fluid (mL)	n = 35	n = 34
mean ± SD	136.1 ± 74.5	201.4 ± 81.0	4.595	< 0.001
Range	20-400	50-800
Gastric tube indwelling duration (d)
mean ± SD	2.7 ± 1.0	3.3 ± 1.6	2.390	0.018
Mean peritoneal drainage volume (mL)	n = 61	n = 59
mean ± SD	165.9 ± 73.1	203.1 ± 99.2	2.395	0.018
Range	50-350	80-550
Drainage tube indwelling duration (d)
mean ± SD	4.1 ± 1.0	5.0 ± 1.8	3.365	0.001

Table 4 Drainage volume of chyle after the operation in the trial group and the control group

	Trial group (n = 61)	Control group (n = 59)	Statistic value	P-value
Peritoneal drainage volume (mL)
mean ± SD	258.3 ± 60.1	388.9 ± 63.7	2.745	0.041
Range	210.0-360.0	330.0-510.0
Drainage duration (d)
mean ± SD	7.7 ± 2.5	15.8 ± 4.4	2.800	0.038
Range	5.0-10.0	11.0-20.0

Table 5 Post-operative amylase in blood and drainage fluid and peritoneal drainage volumes of patients with pancreatic fistula in the study group and the control group

	Day 1 post-operation		Day 3 post-operation		Day 5 post-operation
	Study group (n = 8)	Control group (n = 7)	Study group (n = 8)	Control group (n = 7)	Study group (n = 8)	Control group (n = 7)
Serum amylase	165.1 ± 40.2	179.1 ± 64.2	79.0 ± 33.4	107.8 ± 45.2	49.0 ± 22	80.7 ± 48.8
	t value = 0.577	P = 0.572	t value = 1.590	P = 0.130	t value = 1.853	P = 0.081
Drainage volume	191.0 ± 61.2	281.7 ± 106.4	171.1 ± 44.0	224.0 ± 54.6	120.0 ± 64.1	178.9 ± 47.6
	t value = 2.309	P = 0.034	t value = 2.308	P = 0.034	t value = 2.251	P = 0.038
Amylase in drainage fluid	808.6 ± 133.5	1108.6 ± 246.9	388.0 ± 154.5	630.3 ± 215.0	108.4 ± 72.1	134.6 ± 92.6
	t value = 2.521	P = 0.022	t value = 2.532	P = 0.025	t value = 0.616	P = 0.549